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SELECTBIO Conferences Screening Europe

Jens Peter von Kries's Biography

Jens Peter von Kries, Head of Screening, FMP/Leibniz Institute for Molecular Pharmacology

1991 Ph.D., University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany (Molecular Biology)
1991-1995 Postdoc, UKE, research on chromatin organization by nuclear matrix proteins
1995-2000 Postdoc in group of W. Birchmeier, research on Wnt-signaling and protein interactions
2000-2003 Head of Screening Unit at Semaia Pharmaceuticals, Berlin-Dortmund (DE)-Utrecht (NL)
2003-2014 Head of Screening Unit at FMP, Berlin
SF-CAST Norway, Scientific Advisory Board (2011-2014)
Head of joint sections in Chemical Biology at DECHEMA, Frankfurt (since 2012)
My research team serves for assay development and optimization to enable for drug screening with biochemical and cellular test systems in high-throughput. A major focus is on the development of automated object identification routines to support for high-content screening with cellular model systems for cancer development and metastasis. Furthermore we broaden the portfolio of detection systems to serve for academic guest projects to enable for systematic use of bioactive compounds to explore the molecular function of biological systems in heath and disease. Highlights of our collaboration projects demonstrate that approved drugs for diseases like depression or others are capable to kill aggressive lymphomas or rescue heart development in zebrafish. Moreover we identified bioactive compounds which interfere with Wnt dependent tumor development or with Met induced metastasis.

Jens Peter von Kries Image

Open Access HTS Technology Platform for Drug Screening and Genome-wide RNAI

Wednesday, 18 February 2015 at 16:45

Add to Calendar ▼2015-02-18 16:45:002015-02-18 17:45:00Europe/LondonOpen Access HTS Technology Platform for Drug Screening and Genome-wide RNAIScreening Europe in Berlin, GermanyBerlin,

The Chemical Biology platform of the Leibniz-Institut fuer Molekulare Pharmakologie (FMP, Berlin) has set up a Chemical Biology platform supporting by HTS and by Medicinal Chemistry for support of academic projects and SMUĀ“s. Since 2004 the platform supported more than 200 projects. Highlights are the identification of drugs, which interfere with tumor development, metastasis and with malformation of the heart in Zebrafish. A broad portfolio of detection systems (automated microscopes, impedance measurements, high-speed kinetic imaging and flow-cytometry measurement..) is provided for drug screening or genome-wide RNA-interference. The talk provides an overview about technologies and project highlights.

Add to Calendar ▼2015-02-17 00:00:002015-02-18 00:00:00Europe/LondonScreening EuropeScreening Europe in Berlin, GermanyBerlin,