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SELECTBIO Conferences Advances in qPCR

Mark Behlke's Biography



Mark Behlke, Vice President/Chief Scientific Officer, Integrated DNA Technologies Inc

As the Chief Scientific Officer, Dr. Behlke has directed research activities at IDT since joining the company in 1995 with a focus on novel molecular biology applications of oligonucleotide-based technologies. In addition, Dr. Behlke (together with Dr. John Rossi, from the Beckman Research Institute at the City of Hope) is a scientific co-founder of Dicerna Pharmaceuticals, located in Boston, Massachusetts and is a member of the Dicerna Scientific Advisory Board.
Before joining IDT, Dr. Behlke was a Physician Postdoctoral Fellow of the Howard Hughes Medical Institute at the Whitehead Institute for Biomedical Research, MIT, where he studied human sex determination in the laboratory of Dr. David Page. He was a Resident Physician in Internal Medicine and Fellow in Endocrinology at Brigham and Women’s Hospital, Boston. Dr. Behlke received his M.D. and Ph.D. degrees from Washington University, St. Louis in 1988, where he studied immunogenetics in the laboratory of Dr. Dennis Loh. He received his B.S. degree from the Massachusetts Institute of Technology in 1981.
Mark A. Behlke is an inventor on over 30 issued US patents, has numerous pending patent applications, and is an author on over 100 scientific publications and book chapters. He is an internationally recognized expert in nucleic acid technologies and is on the editorial board of leading journals in the field, including Molecular Therapy, Molecular Therapy - Nucleic Acids, and Nucleic Acid Therapeutics.

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Improved PCR using blocked-cleavable primers and thermostable RNase H2

Thursday, 19 April 2012 at 11:45

Add to Calendar ▼2012-04-20 11:45:002012-04-20 12:45:00Europe/LondonImproved Design of Anti-miRNA OligonucleotidesSELECTBIOenquiries@selectbiosciences.com

IDT has developed an amplification method called rhPCR that employs blocked primers which are non-functional until activated by RNase H2 mediated cleavage. rhPCR reduces primer-dimer formation, enabling higher levels of multiplexing. It also improves SNP discrimination and has utility in genotyping and rare-allele detection.


Add to Calendar ▼2012-04-19 00:00:002012-04-20 00:00:00Europe/LondonAdvances in qPCRSELECTBIOenquiries@selectbiosciences.com