Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences Liquid Biopsies and Minimally-Invasive Diagnostics 2017

Ian Papautsky's Biography



Ian Papautsky, Professor, Department of Bioengineering, University of Illinois at Chicago

Dr. Papautsky is Professor in the Department of Bioengineering at the University of Illinois at Chicago. He received the B.S. degree in biomedical engineering from Boston University in 1995 and the Ph.D. degree in bioengineering from the University of Utah in 1999. His current research focuses on use of microfluidics in cell separations and point-of-care sensor systems. He is a member of the DARPA Microfluidic Fundamental Focus (MF3) Center, and a founding member of The Ohio Center for Microfluidic Innovation (OCMI). He received BioOhio 30 in their 30 Award in 2007.

Ian Papautsky Image

Isolation of Cells from Undiluted Whole Blood Using Inertial Microfluidics

Thursday, 5 October 2017 at 14:00

Add to Calendar ▼2017-10-05 14:00:002017-10-05 15:00:00Europe/LondonIsolation of Cells from Undiluted Whole Blood Using Inertial MicrofluidicsLiquid Biopsies and Minimally-Invasive Diagnostics 2017 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Inertial microfluidics is receiving considerable attention for applications in cell separation and liquid biopsy.  However, while these devices have been widely explored for cell separation, sample dilution is necessary. Here, we report on a novel approach to achieve cell separation directly from unprocessed whole blood based solely on cell size.  The separation is achieved through coupling of inertial effects with shear-induced diffusion. Our results from high-speed imaging reveal that focusing of larger cells near the channel centerline is possible, leading to easy separation. Whole blood spiked with fluorescently labeled beads and cells was used to demonstrate the separation principle and its performance without any sample pretreatment. Results confirm the high quality of performance in terms of efficiency (>90%) and RBC rejection rate (>96%).  This work also successfully demonstrates the use of an inertial microfluidic device as a laboratory tool for sorting target cells from undiluted whole blood.


Add to Calendar ▼2017-10-05 00:00:002017-10-06 00:00:00Europe/LondonLiquid Biopsies and Minimally-Invasive Diagnostics 2017Liquid Biopsies and Minimally-Invasive Diagnostics 2017 in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com