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SELECTBIO Conferences Cell & Gene Therapy Asia 2019

Shin-ichi Muramatsu 's Biography

Shin-ichi Muramatsu , Professor of Neurology, Jichi Medical University (JMU)

Shin-ichi Muramatsu is currently a Professor of Neurology at Jichi Medical University (JMU) in Japan. He is also a Project Professor of Center for Gene & Cell Therapy at The Institute of Medical Science, The University of Tokyo. He received his M.D. and Ph.D. from JMU. He was a visiting associate at National Institutes of Health in USA from 1995 to 1997. His research interest is gene and cell therapies for neurodegenerative diseases. His expertise has contributed to a clinical trial of gene therapy for AADC deficiency in both Taiwan and Japan. He received the Award for Excellent Research (2001) and the TAKARA Bio Award (2011) from the Japan Society of Gene Therapy. He is one of the founding members of Gene Therapy Research Institution Co., Ltd.

Shin-ichi Muramatsu  Image

Gene Therapy For Neurological Diseases

Tuesday, 12 November 2019 at 09:40

Add to Calendar ▼2019-11-12 09:40:002019-11-12 10:40:00Europe/LondonGene Therapy For Neurological DiseasesCell and Gene Therapy Asia 2019 in Kobe, JapanKobe,

Adeno-associated virus (AAV) vectors have been widely used for gene therapy. In Clinical studies on advanced Parkinson’s disease, investigators, including us, have shown the motor symptoms to be ameliorated along with an increased dopaminergic activity on positron emission tomography after gene transfer of aromatic L-amino acid decarboxylase (AADC) into the putamen. The beneficial effects of AADC gene transfer have also been shown in children with AADC deficiency. AAV vectors can achieve global transduction of the central nervous system by intravenous or intrathecal injection. We have been developing gene therapy for various diseases including sporadic amyotrophic lateral sclerosis, spinocerebellar ataxia 1, glucose transporter 1 deficiency, and GM2 gangliosidosis.

Add to Calendar ▼2019-11-11 00:00:002019-11-12 00:00:00Europe/LondonCell and Gene Therapy Asia 2019Cell and Gene Therapy Asia 2019 in Kobe, JapanKobe,