| Conferences \ Lab-on-a-Chip and Microfluidics World Congress 2018 \ Lab-on-a-Chip and Microfluidics: Companies, Technologies and Commercialization "Track B" \ Agenda \ Shoji Takeuchi |
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Microfluidics For Biohybrid DevicesWednesday, 3 October 2018 at 16:00  Add to Calendar ▼2018-10-02 16:30:002018-10-02 17:30:00Europe/LondonTitle to be Confirmed.SELECTBIOenquiries@selectbiosciences.comIn this presentation, I will talk about several approaches to develop MEMS/Microfluidic devices combined with living materials for various biomedical sensing and healthcare applications. Living materials show superior functions to the artificial ones such in terms of the ability to recognize/produce biomolecules. For example, membrane proteins achieve highly-sensitive and selective detection of several chemicals at the molecular level; they can even distinguish between different chemical moieties found in various odorants. When a certain ion channel activating a single ligand molecule opens for 1 s under a 100 mV-membrane potential, the number of monovalent ions that are transferred through the ion channel reaches the 106-107 level and generates a few pico-amperes. This reaction means that chemical signals are converted to amplified current signals in living systems; the system can be regarded as a transistor with an excellent amplifier. Here, one of my talk will include our approaches toward biohybrid sensors: a microdevice having membrane proteins (receptors) reconstituted into cells or planar lipid bilayers. We believe that the devices are useful for a highly-selective and rapid detection of various chemicals including drugs, odorants and tastants. This approach is likely to lead to a wide variety of applications including environmental monitoring, food control, and highly-sensitive diagnostic tools. |
Add to Calendar ▼2018-10-01 00:00:002018-10-03 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics: Companies, Technologies and Commercialization "Track B"SELECTBIOenquiries@selectbiosciences.com
