Kevin Plaxco,
Professor,
University of California-Santa Barbara
Kevin Plaxco is a Professor at the University of California, Santa Barbara, with shared appointments between the Department of Chemistry and Biochemistry, the Department of Mechanical Engineering, and the Biomolecular Science and Engineering Graduate Program. Prof. Plaxco also serves as Associate Director of campus’s Center for Bioengineering. Prior to joining UCSB in 1998 Dr. Plaxco received his Ph.D. from Caltech and performed postdoctoral studies at Oxford and the University of Washington. Dr. Plaxco’s research focus is on the physics of biomolecular folding and its engineering applications. A major aim of the group’s applied research is to harness the speed and specificity of folding in the development of sensors, adaptable surfaces, and smart materials. Dr. Plaxco has co-authored more than 200 papers and a dozen patents on protein folding, protein dynamics, and folding-based sensors, and is recognized by Thomson Reuters as one of the most highly cited chemists of the prior decade. He serves on the scientific boards of a half dozen biotechnology firms (several of which are commercializing technologies developed by his group), and has also written a popular science book on Astrobiology.
E-DNA: A Versatile Electrochemical Platform for Point-of-Care Molecular Measurement
Thursday, 18 September 2014 at 14:00
Add to Calendar ▼2014-09-18 14:00:002014-09-18 15:00:00Europe/LondonE-DNA: A Versatile Electrochemical Platform for Point-of-Care Molecular MeasurementPoint-of-Care Diagnostics World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
The ideal sensor will be sensitive, specific, versatile, small enough to hold in your hand, and selective enough to work even when faced with complex, contaminant-ridden samples. Given the affinity, specificity and generalizability of biomolecular recognition, biosensors have been widely touted for their potential to meet these challenging goals. To date, however, the translation of protein- and nucleic acid-binding events into convenient, highly selective sensing platforms has proven problematic. We have solved this problem by employing the ligand-induced folding of biopolymers as a robust means of transducing binding events into specific, easily detected outputs. Our electronic, folding-based sensors are rapid (minutes to seconds), sensitive (micromolar to femtomolar), and generalizable to an enormous range of protein, nucleic acid and small molecule targets. The sensors are also reagentless, reusable, and selective enough to be employed in blood serum, soil and other grossly contaminated samples. Because of their sensitivity, background suppression, operational convenience and impressive scalability folding-based biosensors appear ideally suited for diagnostics at the point of care and in the developing world.
Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonPoint-of-Care Diagnostics World CongressPoint-of-Care Diagnostics World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2014-09-18 14:00:002014-09-18 15:00:00Europe/LondonE-DNA: A Versatile Electrochemical Platform for Point-of-Care Molecular MeasurementPoint-of-Care Diagnostics World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
