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SELECTBIO Conferences Academic Discovery Workshop

Chris Porter's Biography



Chris Porter, Assistant Professor / Pediatrics, University of Colorado School of Medicine

Dr. Porter is a pediatric hematologist-oncologist with extensive training in basic, translational and clinical research. His laboratory focuses on pediatric cancer, and primarily leukemia. They have optimized and used genome-wide and targeted shRNA libraries to identify novel therapeutic strategies for leukemia. For example, they screened the genome in acute myeloid leukemia (AML) cells to identify synthetic lethality with cytarabine, one of the most important conventional agents currently used to treat AML. They found that inhibition of the cell cycle checkpoint protein, Wee1, is synergistic with cytarabine in killing AML cells. He is collaborating with Medical Hematology-Oncologists to develop a clinical trial testing this strategy in humans with the first in class Wee1 inhibitor, AZ1775.

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RNAi Screens to Identify Novel Therapeutic Strategies for Leukemia: Going All The Way

Tuesday, 23 September 2014 at 10:30

Add to Calendar ▼2014-09-23 10:30:002014-09-23 11:30:00Europe/LondonRNAi Screens to Identify Novel Therapeutic Strategies for Leukemia: Going All The WayAcademic Discovery Workshop in Baltimore, MD, USABaltimore, MD, USASELECTBIOenquiries@selectbiosciences.com

Genome-scale RNA-interference screens are used as an unbiased approach to address numerous biological questions, including for the identification of novel therapeutic strategies for cancer. We will present our experience with genome-scale RNAi screens, which have led to clinical trial design and implementation.


Add to Calendar ▼2014-09-23 00:00:002014-09-25 00:00:00Europe/LondonAcademic Discovery WorkshopAcademic Discovery Workshop in Baltimore, MD, USABaltimore, MD, USASELECTBIOenquiries@selectbiosciences.com