Targeting Protein-protein Interactions in the DNA Damage ResponseWednesday, 24 September 2014 at 10:00 Add to Calendar ▼2014-09-24 10:00:002014-09-24 11:00:00Europe/LondonTargeting Protein-protein Interactions in the DNA Damage ResponseAcademic Discovery Workshop in Baltimore, MD, USABaltimore, MD, USASELECTBIOenquiries@selectbiosciences.com Historically, the protein-protein interaction (PPI) target class has been rather underexplored with respect to identifying small molecule inhibitors. We have targeted a DUB-E2 enzyme interaction to modulate DNA damage response. We are able to show specific and selective compound effects in vitro and in the cellular context. |