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SELECTBIO Conferences Gene Silencing & Epigenetics

Aldo Roccaro's Biography

Aldo Roccaro, Senior Scientist, Dana Farber Cancer Institute

Aldo M. Roccaro, M.D., Ph.D. is a Senior Scientist, at Harvard Medical School, Boston, MA. He completed his M.D. degree at Bari Medical School, Bari, Italy, and joined the Dana-Farber Cancer Institute as postdoctoral fellow in 2004. Prior to this, he was fellow in Hematology/Oncology at the University of Bari, Bari, Italy; and at the Unit of Blood Diseases and Cell Therapies, University of Brescia Medical School, Brescia, Italy. Dr. Roccaro’s research mainly focuses on B cell malignancies. Specific areas of interests are neoangiogensis in Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM). He has been recently pioneering work on microRNAs in WM and MM, contributing to major advances in understanding the role of epigenetic modification that lead to the initiation and progression of MM and WM. Dr. Roccaro is recipient of several Awards (Italian Association for Cancer Research, Berlucchi Foundation, ASH, EHA, The Doctors’ Cancer Foundation, Claudia Adams Barr, Accademia Nazionale dei Lincei). Under the mentorship of extremely well know experts in the field of WM and MM (Drs. F. Dammacco, A. Vacca, K.C. Anderson, I.M. Ghobrial, S.P. Treon), he has authored more than 90 manuscripts in peer-reviewed literature and has written nine books chapters in hematology/oncology textbooks. He also contributed to the English to Italian translation of the “Netter’s Clinical Anatomy”.

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Exosome-mediated Transfer of microRNAs Plays a Crucial Role in Multiple Myeloma Pathogenesis

Wednesday, 30 April 2014 at 11:30

Add to Calendar ▼2014-04-30 11:30:002014-04-30 12:30:00Europe/LondonExosome-mediated Transfer of microRNAs Plays a Crucial Role in Multiple Myeloma

It is known that cell-to-cell communication is partially mediated by exosomes. However, it has not been conclusively demonstrated the role of bone marrow mesenchymal stromal cell (BM-MSC)-derived exosomes in supporting hematologic tumor growth and progression, through transfer of their microRNA content to the tumor clone. We therefore dissected the role of exosomal BM-MSC-microRNAs in regulating MM pathogenesis.

Add to Calendar ▼2014-04-29 00:00:002014-04-30 00:00:00Europe/LondonGene Silencing and