Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences Innovations in Microfluidics 2020

Joshua Levin's Biography



Joshua Levin, Senior Group Leader, Research Scientist, Stanley Center for Psychiatric Research, Klarman Cell Observatory, The Broad Institute of MIT and Harvard

Joshua Levin is a senior group leader and research scientist in the Broad Institute of MIT and Harvard’s Stanley Center for Psychiatric Research, as well as in the Klarman Cell Observatory. In his research, he uses transcriptomic approaches to improve our understanding of brain function as it relates to psychiatric disorders such as autism and schizophrenia. During his time at the Broad Institute, he has developed and comprehensively evaluated an extensive portfolio of RNA sequencing (RNA-Seq) methods such as targeted, strand-specific, total, and low-input RNA-Seq protocols. These RNA-Seq methodologies are being used for a variety of projects institute-wide, notably cancer transcriptomics, single cell studies, and genome annotation.

Before joining the Broad Institute in 2007, Levin worked for ten years in the biotechnology industry, first at Syngenta (formerly Ciba-Geigy and Novartis) and later at Novartis Pharmaceuticals using model organisms in functional genomics studies.

Joshua Levin Image

A Systematic Comparison of Single Cell RNA-Seq Methods

Tuesday, 24 March 2020 at 14:00

Add to Calendar ▼2020-03-24 14:00:002020-03-24 15:00:00Europe/LondonA Systematic Comparison of Single Cell RNA-Seq MethodsInnovations in Microfluidics 2020 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com

A multitude of single-cell RNA sequencing methods have been developed in recent years, with dramatic advances in scale and power, and enabling major discoveries and large scale cell mapping efforts. We directly compared seven methods for single cell and/or single nucleus profiling from three types of samples – cell lines, peripheral blood mononuclear cells and brain tissue. To analyze these datasets, we developed and applied scumi, a flexible computational pipeline that can be used for any scRNA-seq method. We evaluated the methods for both basic performance and for their ability to recover known biological information in the samples.


Add to Calendar ▼2020-03-23 00:00:002020-03-24 00:00:00Europe/LondonInnovations in Microfluidics 2020Innovations in Microfluidics 2020 in Boston, USABoston, USASELECTBIOenquiries@selectbiosciences.com