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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics: Companies, Technologies and Commercialization "Track B"

Martyn Boutelle's Biography

Martyn Boutelle, Professor of Biomedical Sensors Engineering, Vice Chair Department of Bioengineering, Imperial College London

Martyn Boutelle is Professor of Biomedical Sensors Engineering, and Deputy Departmental Chair at the Department of Bioengineering, Imperial College London. His research group is genuinely multidisciplinary comprising, bioengineers, scientists and clinicians. He develops novel analytical science methods using microfluidics, electrochemical sensors and biosensors, and wireless electronics to make portable, wearable monitoring devices. He then uses these in a program of clinical science research focusing on the acute traumatic brain injury, kidney transplantation and athelete monitoring. The same measurement techniques are used in patients and in experimental models allowing genuine translational research. Professor Boutelle is a Fellow of the Royal Society of Chemistry. He obtained a BSc and PhD in Chemistry from Imperial College and worked as an EP Abraham Research Fellow in the University of Oxford.

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Wearable Microfluidics For Real-Time Personal Monitoring

Monday, 1 October 2018 at 14:30

Add to Calendar ▼2018-10-01 14:30:002018-10-01 15:30:00Europe/LondonWearable Microfluidics For Real-Time Personal

Tissue functions at a cellular level by exchange of molecules either between cells and blood or between the cells themselves. This produces patterns of molecular change that are diagnostic of cellular processes whose origin can be physiological (exhaustion, pregnancy) or pathological (ischemia, renal failure, cancer). Our technologies have now developed to a point where we can aspire to do more than this, to measure from patients in real-time. The has the great benefit that it is them possible to understand the evolution of disease, the effectiveness of treatments, and ultimately to guide treatment. In this presentation I will describe the development of microfluidic devices connected to wireless electronics for transplant organ, patient and athlete monitoring. Tissue sampling is via an integrated microfluidic device, a microdialysis probe. Molecular biomarkers are measured using microscale integrated amperometric biosensors and solid-contact ion-selective electrodes (ISE) for tissue ionic balance. For detailed patterns of ionic responses we have developed  high density Field Effect Transistor (FET) array which function as ISEs within the flow stream. We have also edevelodp multiphase  flow microfluidic systems for highest time resolution.The presentation with describe the design and optimization challenges and include clinical examples from our recent work.

Add to Calendar ▼2018-10-01 00:00:002018-10-03 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics: Companies, Technologies and Commercialization "Track B"