Martyn Boutelle,
Professor of Biomedical Sensors Engineering,
Imperial College London
Martyn Boutelle is Professor of Biomedical Sensors Engineering in the Department of Bioengineering, Imperial College London, and Associate Provost for Estates Planning for Imperial College. His research group is multidisciplinary comprising, bioengineers, scientists, and clinicians. He develops novel analytical science methods using microfluidics, electrochemical sensors / biosensors, and wireless electronics to make portable (sometimes wearable) monitoring devices for use as point of care devices that typically giving continuous real -time displays. He then uses these in a program of clinical science research focusing on the acute traumatic brain injury including that caused by cardiac arrest, neonatal continuous monitoring and kidney transplantation monitoring. He runs the EPSRC funded Bio-nanofabrication suite designed to make microfluidic and biosensor biosensors using scalable methods to allow use in proof-of-concept clinical trials.
Martyn is past president of the International Society for Monitoring Molecules in Neuroscience, and a founder of the COSBID organization for studying acute human brain injury. He published > 190 papers, chapters and patents. He obtained a BSc and PhD in Chemistry from Imperial College and worked as an EP Abraham Research Fellow in the University of Oxford.
Biosensors, Sensors and Microfluidic Devices – Key Technologies to Enable Real-Time Patient Monitoring and Treatment
Tuesday, 10 October 2017 at 12:15
Add to Calendar ▼2017-10-10 12:15:002017-10-10 13:15:00Europe/LondonBiosensors, Sensors and Microfluidic Devices – Key Technologies to Enable Real-Time Patient Monitoring and TreatmentBiodetection and Biosensors 2017 in Murray Edwards College, Cambridge, UKMurray Edwards College, Cambridge, UKSELECTBIOenquiries@selectbiosciences.com
Clinical practice is beginning to wake upto the potential of real-time molecular information from venerable tissue as a means to understand the progression in the tissue of injury or disease. Such patterns of molecular changes, particularly when combined with paternal of physical of electrical signatures, offer the exciting possibility of allowing clinicians to guide therapy on an individualized basis in real time. Microfluidic lab-on-chip devices coupled to tissue sampling using microdialysis provide an important new way for measuring real-time chemical changes as the low volume flow rates of microdialysis probes are ideally matched to the length scales of microfluidic devices. In this presentation I will describe the combination of miniature electrochemical sensors and biosensors with 3D printed microfluidic devices for transplant organ and patient monitoring. Concentrations of key biomarker molecules can then be determined continuously using either optically or electrochemically, using amperometric, potentiometic and array sensors. Wireless devices allow analysis to take place close to the patient. Droplet-based microfluidics, by digitizing the dialysis stream into discrete low volume samples, both minimizes dispersion allowing very rapid concentration changes to be measured, and allows rapid transport of samples between patient and analysis chip. This talk will overview successful design, optimization, automatic-calibration and use of both continuous flow and droplet-based microfluidic analysis systems for real-time clinical monitoring, using clinical examples from our recent work.
Add to Calendar ▼2017-10-10 00:00:002017-10-11 00:00:00Europe/LondonBiodetection and Biosensors 2017Biodetection and Biosensors 2017 in Murray Edwards College, Cambridge, UKMurray Edwards College, Cambridge, UKSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2017-10-10 12:15:002017-10-10 13:15:00Europe/LondonBiosensors, Sensors and Microfluidic Devices – Key Technologies to Enable Real-Time Patient Monitoring and TreatmentBiodetection and Biosensors 2017 in Murray Edwards College, Cambridge, UKMurray Edwards College, Cambridge, UKSELECTBIOenquiries@selectbiosciences.com
