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SELECTBIO Conferences Molecular Medicine Congress
Conferences  \  Molecular Medicine Congress  \  Agenda  \  Stephen Pennington
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Stephen Pennington's Biography


Stephen Pennington, Professor, University College Dublin

Steve is currently Professor of Proteomics in the School of Medicine and Medical Science and the UCD Conway Institute of Biomolecular and Biomedical Research at University College Dublin. He is a lead investigator in the Dublin based ‘Prostate Cancer Research Consortium’ and a member of the first Global Action Plan initiative launched by Movember. His team (www.biomedicalproteomics.org) work closely with clinical colleagues to apply label-free LC-MS strategies to discover protein biomarkers to meet specific unmet needs in specific disease areas. To progress these biomarkers to potential clinical diagnostic assays he has established a dedicated mass spectrometry laboratory for targeted multiplexed protein biomarker measurement and clinical evaluation.

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Multiplexed Measurement of Disease Biomarkers by Mass Spectometry (MRM) for Predictive and Prognostic Purposes

Wednesday, 4 September 2013 at 08:00

Add to Calendar ▼2013-09-04 08:00:002013-09-04 09:00:00Europe/LondonMultiplexed Measurement of Disease Biomarkers by Mass Spectometry (MRM) for Predictive and Prognostic Purposes Molecular Medicine Congress in Frankfurt, GermanyFrankfurt, GermanySELECTBIOenquiries@selectbiosciences.com

The application of a range of proteomics strategies has resulted in the discovery of very large numbers of potential new protein biomarkers but few have reached clinical utility for (a) understanding the molecular mechanisms of disease pathogenesis, (b) identifying new therapeutic targets, or (c) implementing biomarker based personalised treatment.    Some of the challenges faced in the protein biomarker development process and potential solutions will be described from our recent studies on prostate cancer and psoriatic arthritis. In these on-going collaborative projects we are developing a ‘clinical question focused’  pipeline for candidate protein biomarker assembly and validation of 'protein biomarker signatures' by multiple reaction monitoring (MRM). The potential of this approach for the delivery of more personalised patient treatment will be discussed.  

Add to Calendar ▼2013-09-03 00:00:002013-09-04 00:00:00Europe/LondonMolecular Medicine CongressMolecular Medicine Congress in Frankfurt, GermanyFrankfurt, GermanySELECTBIOenquiries@selectbiosciences.com


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