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SELECTBIO Conferences EV-based Diagnostics, Delivery & Therapeutics

Fatah Kashanchi's Biography



Fatah Kashanchi, Professor, George Mason University

Dr. Kashanchi is a Professor and currently at head of the Laboratory of Molecular Virology at the George Mason University. He has obtained more than $15.8 M in funding (NIH, DOD, DOE, and Keck) since his departure from NIH’s intramural program in 2000. He has published more than 218 peer-reviewed manuscripts (h index = 57) and served as an editorial board and reviewer for journals such as JBC, Retrovirology, J. Virol, Virology, NAR, 4 PLoS Journals, Cell, Molecular Cell, Nature Medicine, Nature communications, Scientific Report and Science Translational Medicine.

His lab focuses on understanding the mechanism of viral gene expression in human viruses and how the virus and the host control the dynamics of fundamental machineries needed for viral replication and/or host survival, including pathways that leads to transcription and chromatin remolding using in vitro reconstituted DNA/RNA elements. His lab has also contributed to general understanding of how these machineries are different in T-cells vs. myeloid cells. In recent years, his lab has additionally been focusing on exosomes secreted from HIV and HTLV infected cells, as well as 7 other RNA and DNA virus infections (through collaborations) and validation of data using in vitro functional analysis and humanized mouse models. The more recent exosome works focus on the mechanisms of how autophagy regulates EV biogenesis and how viruses manage to deregulate autophagy. Finally, in collaborations with ATCC, they have purified large-scale iPSC and MSC EVs as reparative agents.

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Add to Calendar ▼2020-02-17 00:00:002020-02-18 00:00:00Europe/LondonEV-based Diagnostics, Delivery and TherapeuticsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com