Suwan Jayasinghe,
Professor of Bioengineering, Centre for Stem Cells and Regenerative Medicine and Department of Mechanical Engineering,
University College London
Professor Suwan Jayasinghe leads the efforts of the BioPhysics Group at University College London. His research has pioneered several direct cell handling platforms for reconstructing multi-cellular three-dimensional architectures mimicking native tissues. These platforms are flexible as they are capable of significantly contributing to three-dimensional cell cryopreservation and culture, generation of human biological models, to the ability to develop practical methods for high throughput screening, drug development to the localized delivery of cells, drugs and tissues for repairing/rejuvenating damaged and dysfunctional tissues and organs. Hence these platforms coupled with experimental and/or medical cells/genes/molecules have revolutionary implications to regenerative biology and medicine.
Novel Scaffolding Approaches for the Biomedical and Clinical Sciences
Wednesday, 18 October 2017 at 10:15
Add to Calendar ▼2017-10-18 10:15:002017-10-18 11:15:00Europe/LondonNovel Scaffolding Approaches for the Biomedical and Clinical SciencesBioprinting and 3D Printing in the Life Sciences Europe in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
Scaffolds are critical for reconstructing a fully cellularised tissue. In this presentation the author presents and discusses the many approaches said to have promise in this endeavour, namely in the reconstruction of tissues, greatly demanded in regenerative medicine. The methods chosen and highlighted in this presentation are based on their perceived promise as postulated in the literature. These methods are further distilled and categorised into either direct and in-direct methods by their ability to either handle the cells and added materials simultaneously or not. Additionally, the author raises another important facet previously not given any thought to, which is - are the cells with other materials truly in three-dimensions to each other? This is critical in the authors perspective as the end goal is for the development of a fully cellularised thick tissue having cells dispersed in three-dimensions to each other for the cells to undergo all expected cellular behaviour as understood through native tissues. Hence keeping the above aspects in mind together with the time and associated costs for the reconstruction of a fully functional tissue each method is critically reviewed elucidating the pros and cons of each approach, and their implications and practicalities to translate into the clinic. Thus, demonstrating the true potential and viability for any approach to move into either the biomedical laboratory and/or the clinic. In coda, the presentation goes onto discussing some significant translational aspects, within the wider aim of regenerative medicine to which these approaches would be able to contribute. The presentation intends to provoke the reader to think practically and realistically about what it might take to develop a technology to reconstruct tissues for repair, replacement and rejuvenation of damaged and/or aging tissues within a clinical environment.
Add to Calendar ▼2017-10-17 00:00:002017-10-18 00:00:00Europe/LondonBioprinting and 3D Printing in the Life Sciences EuropeBioprinting and 3D Printing in the Life Sciences Europe in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2017-10-18 10:15:002017-10-18 11:15:00Europe/LondonNovel Scaffolding Approaches for the Biomedical and Clinical SciencesBioprinting and 3D Printing in the Life Sciences Europe in Cripps Court, Magdalene College, Cambridge, UK Cripps Court, Magdalene College, Cambridge, UK SELECTBIOenquiries@selectbiosciences.com
