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SELECTBIO Conferences Academic Drug Discovery 2015

Susanne Muller Knapp's Biography

Susanne Muller Knapp, Group Head Structural Genomics Consortium (SGC), University Of Oxford

Susanne Müller-Knapp studied Human Biology in Marburg Germany followed by a PhD in molecular biology at the Karolinska Institute in Stockholm, Sweden (1997). She then had more than 6 years of postdoctoral training in the area of inflammation and gene regulation at the Karolinska Institute and at the DIBIT San Raffaele Scientific Institute in Milan, Italy.
In 2004 Susanne joined the Structural Genomics Consortium, SGC, in Oxford. The SGC is an international public private partnership that comprises 9 international pharmaceutical companies and a large network of academic and industrial collaborators. Susanne worked at the SGC first as External Research Manager and then Scientific Coordinator. Currently, she is the Project Manager of the Epigenetic Probe Project, which generates tool compounds with defined specificity and selectivity for epigenetic targets. She also heads the cell based assay group at the SGC testing the cellular activity of the in vitro characterised tool compounds. The focus is on first demonstrating the on-target effect of the characterised compounds in cells to provide a well validated compound. These inhibitors are then used to explore biology and disease relevance of the targets and dissect findings obtained by genetic methods.

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Chemical Probes to Explore Epigenetic Targets

Tuesday, 19 May 2015 at 17:15

Add to Calendar ▼2015-05-19 17:15:002015-05-19 18:15:00Europe/LondonChemical Probes to Explore Epigenetic TargetsAcademic Drug Discovery 2015 in

Chemical probes, well-characterized, potent, selective and cell-active tool compounds, are essential tools in biology and target validation. More than 30 probes against epigenetic targets have been developed by the SGC and provided to the scientific community, which greatly accelerated research in this area.

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