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SELECTBIO Conferences Exosomes and Markers in Biological Fluids

Susanne Gabrielsson's Biography

Susanne Gabrielsson, Associate Professor, Karolinska University Hospital Solna

1. Dr. Gabrielsson has after her PhD in immunology and allergy at Stockholm University and a postdoc on cancer at the Curie Institute in Paris, established a group dedicated to exosome research at the Karolinska Institutet, Sweden. Dr. Gabrielsson focuses her work on the immunological effects of exosomes. She was the first to describe the presence of exosomes in bronchoalveolar lavage fluid, and also in breast milk. She works both with clinical studies and in murine disease models. Her work has revealed that exosomes are major players in lung diseases such as asthma and sarcoidosis. Her work in animal models is giving new insights into how exosome-based cancer vaccines should be designed. The finding that whole protein antigens are loaded onto exosomes, and that MHC molecules on exosomes are of minor importance in T cell activation, paves the way for using allogeneic exosomes as cancer vaccines. Dr Gabrielsson has received a Marie Curie postdoctoral award, the European Academy of Allergology and Clinical Immunology Major Award, The Swedish Medical Society Prize and the Swedish Society For Allergology’s Major Award.

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Exosomes as pro-inflammatory mediators, potential for clinical treatment and as biomarkers.

Tuesday, 16 October 2012 at 14:15

Add to Calendar ▼2012-10-16 14:15:002012-10-16 15:15:00Europe/LondonExosomes as pro-inflammatory mediators, potential for clinical treatment and as

Exosomes are nano-sized natural membrane vesicles which can induce, potentiate, or regulate immune responses depending on their cell of origin. I will describe how exosomes can contribute to inflammatory lung diseases in humans, and describe lessons learnt from mouse experiments.

Add to Calendar ▼2012-10-16 00:00:002012-10-17 00:00:00Europe/LondonExosomes and Markers in Biological