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SELECTBIO Conferences Organ-on-a-Chip Conference

Shannon Stott's Biography

Shannon Stott, Assistant Professor, Massachusetts General Hospital & Harvard Medical School

The Stott laboratory is comprised of bioengineers and chemists focused on translating technological advances to relevant applications in clinical medicine. Specifically, we are interested in using microfluidics and imaging technologies to create tools that increase understanding of cancer biology and of the metastatic process. In collaboration with the Toner, Haber and Maheswaran laboratories, we have developed a microfluidic device that can isolate extraordinary rare circulating tumor cells (CTCs) from the blood of cancer patients. We are striving to employ new imaging modalities to extract as much information as possible from these rare cells while pushing the technology further for early cancer detection. Ultimately, we hope that by working in close partnership with the molecular and cell biologist at the Mass General Cancer Center, we can create new tools that directly impact patient care.

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Microfluidics and Biofabrication Approaches for Interrogation of Circulating Biomarkers

Wednesday, 8 July 2015 at 16:00

Add to Calendar ▼2015-07-08 16:00:002015-07-08 17:00:00Europe/LondonMicrofluidics and Biofabrication Approaches for Interrogation of Circulating

Advances in microfluidic technologies, biomaterials and molecular profiling have propelled the rapid growth and interest in achieving a ‘liquid biopsy’ in cancer. This presentation will discuss the various circulating biomarkers that are currently being isolated using microfluidics and their potential utility in the clinic.  As part of this discussion, an overview will be provided on the three successive generations of microfluidic devices that our team has developed at MGH for the isolation of circulating tumor cells (CTCs) from patient blood. Through improvements with each generation of the CTC-chip, our group has been able to increase our ability to interrogate these rare circulating cancer cells and gain new insights into cancer biology and identify novel biomarkers.

Add to Calendar ▼2015-07-08 00:00:002015-07-09 00:00:00Europe/LondonOrgan-on-a-Chip