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SELECTBIO Conferences Exosomes and Markers in Biological Fluids

Irina Nazarenko's Biography

Irina Nazarenko, Exosome and Tumor Biology Group Leader, University of Freiburg

Irina Nazarenko is head of the Exosome and Tumor Biology Group at the Medical Center University of Freiburg, Germany. The main focus of her group is the role of Extracellular Vesicles (EVs) in metastatic cancer progression and their application in liquid biopsy. Together with her team she is addressing EVs heterogeneity and the relevance of different EV subtypes for metastases. New in vitro system allowing modelling of 3D tumor environment, EVs isolation and study of their function under 3D conditions is one her recent works. She is working on the concept of “high precision liquid biopsy”, addressing the relevance of different EVs subtypes as a biomarker source. Being trained in genetics and molecular biology at the Moscow State University, Irina Nazarenko started to work with EV during her postdoctoral training at the German Cancer Research Center. She is one of the founders of the International Society of Extracellular Vesicles (ISEV) and a founder and general secretary of the German Society of Extracellular Vesicles (GSEV).

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Exosome Content and Their Function in the Metastasizing Breast Carcinomas

Wednesday, 17 October 2012 at 11:45

Add to Calendar ▼2012-10-17 11:45:002012-10-17 12:45:00Europe/LondonExosome Content and Their Function in the Metastasizing Breast

Early diagnosis remains one the major challenges for a successful treatment of the metastasizing breast carcinomas. Our data support that the content of exosomes derived from the breast cancer metastasis differs from those derived from a primary tumor. This change of the exosome content reflects epithelial-mesenchymal transition of the tumor cells and play a deceive role in the regulation of a pro-angiogenic activity of tumor-derived exosomes.

Add to Calendar ▼2012-10-16 00:00:002012-10-17 00:00:00Europe/LondonExosomes and Markers in Biological