Conferences \ Circulating Biomarkers, Exosomes & Liquid Biopsy Europe 2019 \ Agenda \ Bas WM van Balkom |
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Zero Hour Liquid Biopsies from Donor KidneysThursday, 31 October 2019 at 16:45 Add to Calendar ▼2019-10-31 16:45:002019-10-31 17:45:00Europe/LondonZero Hour Liquid Biopsies from Donor KidneysCirculating Biomarkers, Exosomes and Liquid Biopsy Europe 2019 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com Kidney transplantation is the preferred treatment for end-stage kidney disease, and donor kidney shortage urges proper donor-recipient matching. Zero-hour biopsies provide predictive value for short- and long-term transplantation outcome, but are invasive and may not reflect the entire organ. Alternative, more representative methods to predict transplantation outcome are required. We hypothesized that preservation fluid contains proteins and exosomes could serve as biomarkers to predict post-transplantation graft function. We explored their presence and biomarkers potential and confirmed that secreted products in this fluid can be used to predict post-transplantation kidney function. |