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SELECTBIO Conferences Discovery Chemistry Congress

Rob Montfort's Biography

Rob Montfort, Leader, The Institute of Cancer Research

Rob van Montfort joined the Institute of Cancer Research (ICR) in London in 2007 where he set up high-throughput X-ray crystallography to support drug discovery at the Institute’s Cancer Research UK Cancer Therapeutics Unit. He is currently leading the Unit’s Hit Discovery and Structural Design (HDSD) team, which is responsible for hit generation using high-throughput and fragment-based approaches. Previously he worked at Astex Therapeutics in Cambridge, where he was involved in fragment-based drug discovery using X-ray crystallography and nuclear magnetic resonance (NMR).He received his PhD in protein crystallography at the University of Groningen, the Netherlands and has worked as a postdoctoral fellow at the School of Crystallography at Birkbeck College, University of London.

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Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase

Tuesday, 17 February 2015 at 14:45

Add to Calendar ▼2015-02-17 14:45:002015-02-17 15:45:00Europe/LondonDiscovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) KinaseDiscovery Chemistry Congress in Berlin, GermanyBerlin,

The talk focuses on the discovery of potent and selective MPS1 inhibitors, guided by structure-based design and cellular characterization of MPS1 inhibition, resulting in CCT251455, an attractive tool compound to further elucidate the therapeutic potential of MPS1 inhibition

Add to Calendar ▼2015-02-17 00:00:002015-02-18 00:00:00Europe/LondonDiscovery Chemistry CongressDiscovery Chemistry Congress in Berlin, GermanyBerlin,