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SELECTBIO Conferences Structural & Computational Chemistry

Alexander Alex's Biography



Alexander Alex, Director, Alex Alexander Consulting

Alexander Alex is owner of the pharmaceutical consultancy business Alexander Alex Consulting. He has over 18 years experience in the pharmaceutical industry as Director and Research Fellow at Pfizer in Sandwich, United Kingdom, and 24 years experience in the field of Computational Chemistry. He has successfully applied computational approaches to all stages in the drug discovery process from lead seeking to drug candidate nomination, including ADMET rationalisation and prediction. He has over 30 scientific publications and more than 20 invited oral presentations in the areas of computational chemistry, chemoinformatics, structure-based drug design, fragment-based drug design, molecular properties, ADMET as well as prediction of chemical reactivity and mass spectrometry fragmentation. He has a doctorate in Chemistry and is a Fellow of the Royal Society of Chemistry.

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ADMET Rationalisation and Prediction in Drug Discovery: Can Computational Chemistry Reduce Compound Attrition

Wednesday, 14 March 2012 at 11:45

Add to Calendar ▼2012-03-14 11:45:002012-03-14 12:45:00Europe/LondonADMET Rationalisation and Prediction in Drug Discovery: Can Computational Chemistry Reduce Compound Attrition SELECTBIOenquiries@selectbiosciences.com

Compound attrition is one of the major challenges in drug research, impacting productivity and preventing potential new chemical entities reaching the market. Understanding the factors which influence attrition as early as in the compound design stage prior to synthesis is critical for preventing potential ADMET liabilities in compound development. Therefore the effective utilisation of computational approaches to rationalise and predict potential ADMET issues early is crucial in assisting compound designers in understanding, preventing and managing compound attrition risk.


Add to Calendar ▼2012-03-13 00:00:002012-03-14 00:00:00Europe/LondonStructural and Computational ChemistrySELECTBIOenquiries@selectbiosciences.com