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SELECTBIO Conferences BioEngineering Summit 2019

Stephanie Willerth's Biography



Stephanie Willerth, Associate Professor and Canada Research Chair in Biomedical Engineering, University of Victoria

Dr. Willerth holds a Canada Research Chair in Biomedical Engineering at the University of Victoria where she has dual appointments in the Department of Mechanical Engineering and the Division of Medical Sciences as an Associate Professor. She serves as the Acting Director for the Centre for Biomedical Research at the University of Victoria and on the steering committee of the B.C. Regenerative Medicine Initiative. She also served as the President of the Canadian Biomaterials Society from 2017-2018. Her honors include being named the 2018 REACH award winner for Excellence in Undergraduate Research-inspired Teaching, a Woman of Innovation in 2017, one of the 2015 Young Innovators in Cellular and Biological Engineering and a "Star in Global Health" by Grand Challenges Canada in 2014. She spent Fall of 2016 on sabbatical at the Wisconsin Institute for Discovery supported by the International Collaboration on Repair Discoveries International Travel Award where she wrote her book “Engineering neural tissue using stem cells” published by Academic Press. She completed her postdoctoral work at the University of California-Berkeley after receiving her Ph.D. in Biomedical Engineering from Washington University. Her undergraduate degrees were in Biology and Chemical Engineering from the Massachusetts Institute of Technology.

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3D Bioprinting Tools For Engineering Complex Neural Tissues From Stem Cells

Monday, 1 April 2019 at 09:00

Add to Calendar ▼2019-04-01 09:00:002019-04-01 10:00:00Europe/London3D Bioprinting Tools For Engineering Complex Neural Tissues From Stem CellsSELECTBIOenquiries@selectbiosciences.com

3D bioprinting can create living human tissues on demand based on specifications contained in a digital file. Such highly customized, physiologically-relevant 3D human tissue models can screen potential drug candidates as an alternative to expensive pre-clinical animal testing. The Willerth lab has developed a novel fibrin-based bioink for bioprinting neural tissues derived from human induced pluripotent stem cells (hiPSCs), which can become any cell type found in the body. Our team uses Aspect Biosystem’s novel RX1 bioprinter featuring Lab-On-a-Printer™ (LOP) technology as it enables us to fabricate complex structures found in healthy neural tissues. The microfluidic LOP™ printhead cartridges generate cell-containing hydrogel fibers of defined diameters that are precisely deposited into defined 3D structures using a sheath fluid that triggers hydrogel cross-linking of the bioink. The sheath fluid also insulates cells within the fiber from shear stress, protecting fragile primary cells from shear-induced cell death. This process allows us to maintain high levels viability (>90% post printing) not previously seen in the literature. Here I will discuss the latest work from our group detailing the composition of our 3D bioprinted tissues and exciting avenues for future work.


Add to Calendar ▼2019-04-01 00:00:002019-04-02 00:00:00Europe/LondonBioEngineering Summit 2019SELECTBIOenquiries@selectbiosciences.com