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SELECTBIO Conferences Biofabrication & Biomanufacturing Europe 2019

Adam Feinberg's Biography

Adam Feinberg, Professor, Carnegie Mellon University

Dr. Feinberg is the principal investigator of the Regenerative Biomaterials and Therapeutics Group and an Associate Professor at Carnegie Mellon University. He earned his BS in Materials Science and Engineering from Cornell University in 1999 with Co-op experience at Abiomed, Inc., working on total artificial hearts. He then earned MS and PhD degrees in Biomedical Engineering from the University of Florida, focused on engineering cell-material interactions to prevent and enhance adhesion. This was followed by postdoctoral training at Harvard University, developing new biomaterials and stem cell-based cardiac tissue engineering strategies. He joined the faculty at Carnegie Mellon in the fall of 2010 with joint appointments in Biomedical Engineering and Materials Science and Engineering. Dr. Feinberg has co-authored over 45 peer-reviewed publications, holds over 20 US patents and patent applications and is Co-Founder and CTO of FluidForm LLC, a 3D bioprinting start-up. He has also been awarded the NSF CAREER Award, the NIH Director’s New Innovator Award, and the American Heart Association Scientist Development Grant. Current research is focused on biomimetic strategies to fabricate ECM protein-based materials from fibronectin, laminin, and collagens type I and IV to build 2D and 3D scaffolds for corneal, skeletal and cardiac tissue engineering. Further, he is working to understand the biomechanics and mechanobiology of these engineered ECM protein materials, specifically how strain modulates biological activity.

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FRESH 3D Printing of Liquid and Soft Materials: New Applications From Regenerative Medicine to Wearable Sensing

Thursday, 20 June 2019 at 12:15

Add to Calendar ▼2019-06-20 12:15:002019-06-20 13:15:00Europe/LondonFRESH 3D Printing of Liquid and Soft Materials: New Applications From Regenerative Medicine to Wearable SensingBiofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The

Over the past decade, 3D bioprinting has rapidly expanded from a niche technology and in to a versatile platform for fabricating tissues with complex geometries and features ranging from the cellular to organ length scales. Recent advances include engineering the 3D cell microenvironment, hierarchical vascular networks in thick tissue constructs and biodegradable tissue scaffolds implanted in animal models and human patients. However, the range of additive manufacturing technologies currently used each has distinct advantages and disadvantages, and specifically it is critical to understand how the resolution of these different approaches dictate structure and function of the engineered tissue constructs. Here we will discuss our recent progress in the additive manufacturing of complex structures using hydrogels and various thermoset resins that are otherwise impossible to additively manufacture using alternative approaches. These structures are built by embedding the printed material within a temporary, thermoreversible, and biocompatible support fluid. This process, termed freeform reversible embedding of suspended hydrogels (FRESH), enables additive manufacturing of hydrogels with an elastic modulus less than 500 kPa. FRESH 3D printing also enables fabrication with thermoset and composite resins such as epoxies, acrylates, and siloxanes, and can host a range of polymerization mechanisms depending on the printed material, including ionic crosslinking, enzymes, pH change, heat/light exposure, and time-sensitive gelation approaches. We will demonstrate recent advances towards a range of new applications, including 3D printing of collagen for bioengineering functional tissue constructs and of silicone elastomers for patient-specific, wearable medical devices. Specific work is focused on cellularized collagen constructs to create functional cardiac tissues and extending these approaches to additional tissue and organ systems for in vitro disease modeling and in vivo regeneration.

Add to Calendar ▼2019-06-20 00:00:002019-06-21 00:00:00Europe/LondonBiofabrication and Biomanufacturing Europe 2019Biofabrication and Biomanufacturing Europe 2019 in Rotterdam, The NetherlandsRotterdam, The