Exosome Biogenesis: Role of Exosomal Cargo in the Production and Secretion of ExosomesThursday, 12 September 2013 at 17:15 Add to Calendar ▼2013-09-12 17:15:002013-09-12 18:15:00Europe/LondonExosome Biogenesis: Role of Exosomal Cargo in the Production and Secretion of ExosomesExosomes and Circulating Biomarkers Summit 2013 in San Diego, CASan Diego, CASELECTBIOenquiries@selectbiosciences.com The molecular information content of exosomes is fundamental to their function. Exosomes, carry cell-type specific cargo targeted for extracellular destinations. While a constitutive synthesis of exosomes is conceivable as part of the cellular basis of tissue homeostasis we assume that the production of exosomes containing cell type-specific gene products may not be random but dictated by tissue physiology and cellular function; exosomes may be assembled and secreted in response to instructions received from the neighboring cells or from distant tissues. Thus an efficient way of coordinating the process of exosome production and secretion, which is temporally precise and functionally relevant, is to have the cell-type specific cargo a role in their biogenesis. |