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SELECTBIO Conferences Circulating DNA, Circulating RNA, Circulating Tumor Cells

Abhijit Patel's Biography

Abhijit Patel, Associate Professor, Yale University School of Medicine

Abhijit Patel’s research group at Yale University is working to develop and develop and clinically validate novel noninvasive DNA- and RNA-based cancer diagnostics. He is an Associate Professor of Therapeutic Radiology at the Yale University School of Medicine. He completed residency training in radiation oncology at Harvard University, medical internship at Memorial Sloan-Kettering Cancer Center, and obtained his MD and PhD degrees at Yale University. His scientific background is in the field of nucleic acid biochemistry, having performed his Ph.D. and postdoctoral training with Drs. Joan Steitz and Jack Szostak. As a physician-scientist, he also maintains an active clinical radiation oncology practice.

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Circulating Tumor DNA as a Noninvasive Marker of Therapeutic Response and Resistance

Monday, 23 March 2015 at 16:30

Add to Calendar ▼2015-03-23 16:30:002015-03-23 17:30:00Europe/LondonCirculating Tumor DNA as a Noninvasive Marker of Therapeutic Response and

Our group has developed an ultrasensitive, multi-target assay that can identify and quantify mutant ctDNA using novel error-suppression techniques applied to next-generation sequencing data.  Broad coverage of mutation hotspots and warm-spots allows detection of ctDNA without prior knowledge of the tumor’s mutation profile.  Clinical examples will be presented in which this approach is being used to noninvasively monitor changes in ctDNA levels in response to treatment and to track the emergence of mutations that confer resistance to targeted therapies.

Add to Calendar ▼2015-03-23 00:00:002015-03-24 00:00:00Europe/LondonCirculating DNA, Circulating RNA, Circulating Tumor