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SELECTBIO Conferences EV-based Diagnostics, Delivery & Therapeutics

Aijun Wang's Biography



Aijun Wang, Chancellor's Fellow Professor, University of California-Davis

Dr. Aijun Wang is a Chancellor's Fellow, Professor of Surgery and of Biomedical Engineering at the University of California, Davis (UC Davis). He is the Vice Chair for Translational Research, Innovation and Entrepreneurship for the Department of Surgery, Co-founder and Co-Director of the Center for Surgical Bioengineering (CSB), formerly known as Surgical Bioengineering Laboratory, and Dean's Fellow in Entrepreneurship at the UC Davis School of Medicine. He is also a Principal Investigator at the Institute for Pediatric Regenerative Medicine (IPRM) / Shriners Hospitals Pediatric Research Center, Northern California. Dr. Wang’s research focuses on developing tools, technologies and products that combine molecular, cellular, tissue and biomaterial engineering to promote regeneration and restore function. Specifically, the Wang Group is focused on engineering and developing stem cell/gene therapy, extracellular vesicles/nanomedicine, and extracellular matrix/biomaterial scaffolds for the treatment of surgical conditions and diseases. Dr. Wang and his team at CSB specialize in bringing therapeutics from bench to bedside, through translational and IND-enabling studies, GMP manufacturing, and conducting clinical trials in both human and companion animal patients.

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Engineering Stem Cell-derived EVs For Local Delivery and Therapeutic Applications

Tuesday, 18 February 2020 at 09:30

Add to Calendar ▼2020-02-18 09:30:002020-02-18 10:30:00Europe/LondonEngineering Stem Cell-derived EVs For Local Delivery and Therapeutic ApplicationsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Extracellular vesicles (EVs) play a significant role in cell-to-cell communication. In our previous studies, we have confirmed that EVs secreted by placental mesenchymal stem cells (PMSC-EVs) exert significant neuroprotective functions similar in magnitude to live PMSCs. In this presentation, I will discuss what we have learned about PMSC-EVs and the potential mechanisms of action on how PMSC-EVs are protecting neurons. Recently, we have also developed various approaches to improve MSC-EV’s yield and efficacy, and designed biomaterials-based delivery vehicles to improve MSC-EVs stability, retention and targeted delivery. In summary, we are developing and engineering stem cell-derived EVs into a cell-free, off-the-shelf, and easy-to-use therapeutic modality for various disease treatment and regenerative medicine applications.


Add to Calendar ▼2020-02-17 00:00:002020-02-18 00:00:00Europe/LondonEV-based Diagnostics, Delivery and TherapeuticsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com