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SELECTBIO Conferences Exosomes and Extracellular Vesicles (EV): Research, Diagnostics and Therapeutics Opportunities

Paul Robbins's Biography



Paul Robbins, Professor, Department of Biochemistry, Molecular Biology, and Biophysics, and the Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School

Paul D. Robbins, Ph.D. is Professor Department of Biochemistry, Molecular Biology, and Biophysics, and the Institute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, MN. Previously he was a Professor of Microbiology and Molecular Genetics, Director of Basic Research for the Molecular Medicine Institute and Co-Director of the Paul Wellstone Cooperative Muscular Research Center at the University of Pittsburgh School of Medicine as well as Interim Director of Molecular & Cellular Oncology at the University of Pittsburgh Cancer Institute. He received his B.A. from Haverford College, his Ph.D. from the University of California at Berkeley and worked as a post-doctoral fellow in the laboratory of Dr. Richard Mulligan at the Whitehead Institute for Biomedical Research at MIT. He has co-authored over 320 peer-reviewed manuscripts and 170 book chapters and reviews and edited four books. He was a member of the NIH PathB Study Section, Chair of the Italian Telethon Scientific Review Committee and a member of the Telethon Scientific Advisory Board. He also was a member of the Scientific Review Board of National Gene Vector Laboratory and the Board of Directors of the American Society of Gene Therapy and currently is a member of the National Institute on Aging Interventions Testing Program. He has co-founded two biotechnology companies and currently serves on the Scientific Advisory Boards of four biotechnology companies. Dr. Robbins’ research is focused on developing therapeutic approaches, including small molecules, biologics and stem cells, to extend healthspan and reduce frailty using mouse models of aging.

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Development of Therapeutic Approaches Using Extracellular Vesicles to Treat Age-Related Diseases

Tuesday, 21 March 2017 at 08:00

Add to Calendar ▼2017-03-21 08:00:002017-03-21 09:00:00Europe/LondonDevelopment of Therapeutic Approaches Using Extracellular Vesicles to Treat Age-Related DiseasesSELECTBIOenquiries@selectbiosciences.com

With aging, there is an inevitable and progressive loss of the ability of tissues to recover from stress, in part through loss of stem cell function. More than 90% of people over 65 years of age have at least one chronic disease, while 75% have at least two. Thus, it is imperative to find a way to target therapeutically the process of aging to compress the period of functional decline in old age. We have demonstrated that injection of adult stem cells isolated from young wild-type mice into a mouse model of accelerated aging conferred significant lifespan and healthspan extension through a paracrine/endocrine mechanism. Moreover, treatment of mice with EVs from young stem cells is able to extend health-span. Progress towards developing clinically relevant approaches using stem cell-derived extracellular vesicles to treat autoimmune and age-related pathologies will be presented.


Add to Calendar ▼2017-03-20 00:00:002017-03-21 00:00:00Europe/LondonExosomes and Extracellular Vesicles (EV): Research, Diagnostics and Therapeutics OpportunitiesSELECTBIOenquiries@selectbiosciences.com