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SELECTBIO Conferences Extracellular Vesicles 2017

Lucia Languino's Biography



Lucia Languino, Professor, Thomas Jefferson University

Dr. Languino investigates the role of cell adhesion receptors in phenotypic changes of prostate cancer cells. A strong research focus is being devoted to the study of the cross-talk between cell adhesion molecules, extracellular matrix proteins and growth factor receptors in vitro and in vivo systems and how this cross-talk affects intracellular signal transduction, cell survival, cell migration and cell division. Dr. Languino's research interests also focus on the cellular and molecular characterization of the metastatic process of prostate cancer with particular emphasis on the signals directing distant localization of prostate cancer cells

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Exosome-Mediated Functional Delivery of Integrins Promotes Cancer Progression

Wednesday, 27 September 2017 at 14:30

Add to Calendar ▼2017-09-27 14:30:002017-09-27 15:30:00Europe/LondonExosome-Mediated Functional Delivery of Integrins Promotes Cancer ProgressionExtracellular Vesicles 2017 in Cripps Court, Magdalene College, Cambridge, UKCripps Court, Magdalene College, Cambridge, UKSELECTBIOenquiries@selectbiosciences.com

Our investigations focus on exosome-mediated transfer of integrin surface receptors among subsets of cancer cells, and among cancer cells and the surrounding microenvironment.

Our recent studies demonstrate that exosomes from cancer cells contribute to horizontal propagation of integrin-associated invasive phenotypes in a paracrine fashion.

The presentation will cover the role of exosomal integrins in cancer progression, and will discuss their potential use as clinical biomarkers for non-invasive diagnosis and/or as therapeutic targets in cancer.


Add to Calendar ▼2017-09-26 00:00:002017-09-28 00:00:00Europe/LondonExtracellular Vesicles 2017Extracellular Vesicles 2017 in Cripps Court, Magdalene College, Cambridge, UKCripps Court, Magdalene College, Cambridge, UKSELECTBIOenquiries@selectbiosciences.com