SELECTBIO - Microfluidics & Organ-on-a-Chip Asia 2019 Biographies

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Construction of Artificial Cell-Membrane System Using Microfluidics

Thursday, 14 November 2019 at 12:00

Add to Calendar ▼2019-11-14 12:00:002019-11-14 13:00:00Europe/LondonConstruction of Artificial Cell-Membrane System Using MicrofluidicsMicrofluidics and Organ-on-a-Chip Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com

Artificial cell membranes have emerged as a biomimetic tool in such areas as membrane protein study, synthetic biology, and drug discovery. Planar lipid bilayers are used for functional studies of ion channels and nanopore sensing. The stability of lipid bilayers and the reproducibility of bilayer formation are important and it still remains challenging. To address these issues, we have used microfabrication and microfluidic technologies that have a major advantage: easy to handle lipid molecules or solution at the micron scale using microfluidics. Applying these advantages, we propose a stable and reproducible preparation procedure for the planar lipid bilayers using “droplet contact method”, and they are applying to measure pore-forming peptides and nanopore sensing.

Ryuji Kawano, Associate Professor, Tokyo University of Agriculture and Technology

Dr. Ryuji Kawano is an Associate Professor at Tokyo University of Agriculture and Technology (TUAT). He received his Ph.D. in 2005 from Yokohama National University, and then he spent 3 years in Prof. Henry S. White’s lab. at the U. of Utah, where he conducted research on nanopore measurements. He then joined Prof. S. Takeuchi’s group at KAST and U. of Tokyo, where he carried out research on the construction of durable lipid bilayer systems using microfabricated devices. Since 2014 he worked as an associate professor at the present university. His current research interests include molecular robotics based on synthetic membrane proteins, DNA computing, and nanopore technology based on microfabricated technologies.