Progress in Advanced 3D Printing for Microfluidics

Wednesday, 29 November 2023 at 14:00

Add to Calendar ▼2023-11-29 14:00:002023-11-29 15:00:00Europe/LondonProgress in Advanced 3D Printing for MicrofluidicsLab-on-a-Chip and Microfluidics World Congress 2023 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com

While there is great interest in 3D printing for microfluidic device fabrication, a main challenge has been to achieve feature sizes that are in the truly microfluidic regime (<100 µm). A key issue is that microfluidic devices are comprised primarily of negative space features, which therefore dominate 3D printing resolution requirements, as compared to positive space features that are typical for many other 3D printing applications. Consequently, we have developed our own stereolithographic 3D printers and materials that are specifically tailored to meet these needs. We have shown 3D printed channels as small as 18 µm x 20 µm, and have recently reduced this to 2 µm x 2 µm. We have also developed active elements such as valves and pumps. With these capabilities, we demonstrate highly integrated 3D printed microfluidic devices such as a 10-stage 2-fold serial dilutor that simultaneously creates a 3 order of magnitude range of concentrations, high density chip-to-chip interconnects (53 interconnects per square mm) that are directly 3D printed as part of a device chip, and droplet-on-demand structures to efficiently entrain individual bacteria in relatively few droplets despite initial large sample volume. These advances open the door to 3D printing as a replacement for expensive cleanroom fabrication processes, with the additional advantage of fast (~5-15 minute), parallel fabrication of many devices in a single print run due to their small size.

Gregory Nordin, Professor, Brigham Young University

Gregory Nordin

Professor Greg Nordin joined the faculty of the Electrical & Computer Engineering Department at Brigham Young University in 2005. From 1992 to 2005 he was at The University of Alabama in Huntsville (UAH) where he was the founding director of the university's Nano and Micro Devices Center, which was created as an independent research center by the University of Alabama System Board of Trustees. While director of the center, he created a 7,600 sq. ft. cleanroom facility for nano and microfabricated devices to pursue research activities in photonics, MEMS, microfluidics, and sensors. Prof. Nordin has led numerous large research programs, and has been principal investigator on research grants from government and industry totaling $18M. He is the recipient of the National Science Foundation CAREER award (1996) for promising young faculty, and twice received the UAH Outstanding Researcher Award as well as the UAH Foundation Award for Research and Creative Achievement. Prof. Nordin's current research is focused on developing 3D printing for microfluidic devices and applications. In March 2018 Prof. Nordin gave a TED talk on his group's work, which is available at https://www.youtube.com/watch?v=T122fzOEVYE.