Roger Lasken, Director of Single Cell Genomics, J. Craig Venter Institute

Professor Lasken leads a single cell genomics program at the J. Craig Venter Institute. His group developed the MDA method (sold as TempliPhi, GenomiPhi and REPLI-g) and was the first to sequence DNA from individual cells. Current work in the lab focuses on RNA-seq from single cells and nuclei (Grindberg, R. V. et al. RNA-sequencing from single nuclei, PNAS, USA, doi:10.1073/pnas.1319700110 (2013); Krishnaswami et al., Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons, Nature Protocols (2016), vol. 11, No. 3, 499; Lacar, et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation, Nature Communications (2016) Apr 19;7:11022. doi: 10.1038/ncomms11022. PMID: 27090946.