Michael Schöning,
Professor and Director, Institute of Nano- and Biotechnologies,
Aachen University of Applied Sciences
Michael J. Schöning received his diploma degree in electrical engineering (1989) and his PhD in the field of semiconductor-based microsensors for the detection of ions in liquids (1993), both from the Karlsruhe University of Technology. In 1989, he joined the Institute of Radiochemistry at the Research Centre Karlsruhe. Since 1993, he has been with the Institute of Thin Films and Interfaces (now, Peter Grünberg Institute, PGI-8) at the Research Centre Jülich, and since 1999 he was appointed as full professor at Aachen University of Applied Sciences, Campus Jülich. Since 2006, he serves as a director of the Institute of Nano- and Biotechnologies (INB) at the Aachen University of Applied Sciences. His main research subjects concern silicon-based chemical and biological sensors, thin-film technologies, solid-state physics, microsystem and nano(bio-)technology.
Combined Calorimetric Gas- and Spore-based Biosensor for Aseptic Food Processing
Wednesday, 30 June 2021 at 11:30
Add to Calendar ▼2021-06-30 11:30:002021-06-30 12:30:00Europe/LondonCombined Calorimetric Gas- and Spore-based Biosensor for Aseptic Food ProcessingPoint-of-Care, Biosensors and Mobile Diagnostics Europe 2021 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Gaseous H2O2 represents one of the most used sterilization agents in aseptic food processing. To validate this sterilization method under investigation, robust spores that are resistant against this sterilant are first exposed. Afterwards, the logarithmic kill rate (i.e., how many survived from them) is determined by time-consuming (48-72 h) and tedious microbiological count-plating methods (e.g., count reduction test, end point test). A novel sensing method is introduced, consisting of a spore-based biosensor, which is combined with a calorimetric H2O2 sensor onto a single chip to evaluate both the viability of the spores and to determine the gaseous H2O2 concentration. The calorimetric gas sensor responds to different concentrations of gaseous H2O2 via change of its initial resistance, whereas the spore-based biosensor monitors the spore degradation, depending on the H2O2 concentration detecting the impedance variation. Three different strains of spores were investigated with regard to the H2O2 durability, namely B. atrophaeus DSM 675, B. subtilis DSM 402 and G. stearothermophilus DSM 5934. The two sensor types were combined as sensor array enabling a considerably more specific multi-parameter experience in aseptic filling machines in comparison to isolated microbiological state-of-the-art- or hydrogen peroxide methods.
