Electrical Property Evaluation of Cells Based on Continuous-Flow Electrorotation

Friday, 6 October 2023 at 12:00

Add to Calendar ▼2023-10-06 12:00:002023-10-06 13:00:00Europe/LondonElectrical Property Evaluation of Cells Based on Continuous-Flow ElectrorotationLab-on-a-Chip and Microfluidics Asia 2023 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com

The electric properties of cancer cells reflect their types and drug resistance status. The electrorotation is a non-invasive and label-free technique to obtain the electrical properties of cells, conductivity and permittivity of cytoplasm or membrane, using image analysis of the rotational behavior of the cells under a rotating electric field. However, conventional electrorotation has issues with its low throughput due to difficulties of cell handling. Our research group has developed a novel electrorotation platform enabling multi-cell analysis under continuous-flow conditions. In the developed microfluidic system, the cells receive a vertically-rotating electric field and result in vertical rotation. We investigated the effectiveness of the vertical rotation analysis of cells and confirmed that the proposed electrorotaion device can be used for the measurement of the electrical properties of cancer cells.

Masahiro Motosuke, Professor, Department of Mechanical Engineering, Tokyo University of Science

Masahiro Motosuke

Prof. Masahiro Motosuke is currently a Professor at Department of Mechanical Engineering, Tokyo University of Science, Japan, and Head of Water Frontier Research Center, Research Institute for Science and Technology at the same university. He received his B.S, M.S and Ph.D at Keio University, Japan. Then he started to work in Department of Mechanical Engineering at the Tokyo University of Science as a Assistant Professor and was in Department of Micro-/Nanotechnology in Technical University of Denmark as a Visiting Professor. He joined Department of Mechanical Engineering, Tokyo University of Science as Junior Associate Professor and thereafter Associate Professor. His research interest is in transport phenomena in micro/nanofluidic system, microfluidic cell assay, nanoparticle detection and handling, and interfacial flow control in micro/nanoscopic domain.