Daniel Rabe,
Research Fellow
Dr. Daniel Rabe is a postdoctoral fellow in the lab of Dr. Shannon Stott at Massachusetts General Hospital. He seeks to elucidate crosstalk between tumor and immune cells through extracellular vesicles (EVs) to better understand how some tumors become metastatic and resistant to therapy. Dr. Rabe utilized novel microfluidics to capture and characterize EVs from patient blood to better understand their impact and utility as biomarkers in cancer and other diseases. By comparing EV signatures in patients to the tumor-immune infiltrate, Dr. Rabe seeks to better understand the role EVs play in the process of metastasis and therapy resistance. Additionally, he seeks to understand how signaling pathways in the tumor alter EV biology, and thereby alter the biology of the immune infiltrate.
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