Guang Yao,
Assistant Professor, Molecular/Cellular Biology
Dr. Yao has focused his work and training at studying gene regulatory networks using integrated systems biology approaches. He received his Ph.D. in cancer biology from UW-Madison. As a postdoctoral fellow at Duke working with Drs. Joe Nevins and Lingchong You, Dr. Yao coupled single-cell experiments with mathematical modeling and demonstrated the first natural bistable system in mammalian cells, the Rb-E2F bistable switch that controls the cell cycle entry at the restriction point. After establishing his research laboratory at the University of Arizona, Dr. Yao has developed a series of single-cell experimental systems, coupled with dynamic and statistical modeling, to study control mechanisms underlying mammalian cell fate decisions, particularly, the delicate balance between cell proliferation, quiescence, and death.
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