Andrew Hoffman,
Professor, Director -- Regenerative Medicine Laboratory
Dr. Andy Hoffman is a large animal internist with long-standing interest in regenerative medicine and translational potential of veterinary disease models to improve human and animal health. His lab focuses on the functional relevance of exosomal miR derived from biofluids (e.g. blood, CSF, saliva) to disease pathogenesis. Are exosomes in biofluids directly involved in the initiation or propagation of disease or bystanders which also have strong biomarker potential? His unique approach is to study these phenomena in companion animal disease models which strikingly resemble human conditions. Models that he works with include congestive heart failure secondary to mitral valve prolapse, arrythmogenic right ventricular cardiomyopathy, atopic dermatitis, Crohn’s fistulitis, spinal disc herniation, and cardiac arrest, updated on Dr. Hoffman’s webpage: http://sites.tufts.edu/vetclinicaltrials/regenerative-medicine-stem-cell-trials/.
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