David Cheresh,
Distinguished Professor of Pathology
David Cheresh, PhD, studies the molecular basis of angiogenesis and tumor progression. He spent to early part of his career at The Scripps Research Institute and moved to the UC San Diego Moores Cancer Center in 2005 where he has led efforts to develop new collaborations and programs in clinical and basic science with an emphasis on translational medicine. He is Associate Director for Innovation and Industry Alliances at the Cancer Center, and Vice Chair and Distinguished Professor of Pathology. Dr. Cheresh studies the signaling networks that regulate angiogenesis, tumor stemness, drug resistance and metastasis. He identified that integrin a?ß3 – a receptor on the surface of tumor-associated blood vessels – as a critical biomarker of angiogenesis. More recently his team discovered that this molecule drives tumor stemness, drug resistance and progression. He successfully translated laboratory discoveries into biologically-based drugs that are now in various stages of clinical development.
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