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SELECTBIO Conferences Biosensors, Microfluidics and Lab-on-a-Chip Technologies

Biosensors, Microfluidics and Lab-on-a-Chip Technologies Agenda



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Biosensors, Microfluidics and Lab-on-a-Chip Technologies | Organ-on-a-Chip Europe 2017 | Point-of-Care Diagnostics 2017 | 

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Wednesday, 10 May 2017

08:00

Registration


Day One
Session Chair: Jonas Tegenfeldt, Professor, Lund University, Sweden

09:00

A Microfluidic Culturing and Real Time Monitoring Systems Using Diffusive Nutrition Distribution
Winnie Svendsen, Professor, Technical University of Denmark, Denmark

A microfluidic platform separating nutrient perfusion from the culturing site, thus utilizing diffusive nutrient delivery, has been developed and tested on several cell types and brain slices. The results and future potential of this platform will be presented and discussed.

09:30

David WeitzKeynote Presentation

Single Cell Analysis Using Drop Based Microfluidics
David Weitz, Professor, Harvard University, United States of America

10:15

Microfluidic Platforms Incorporating Design-For-Manufacture and Scale-Up of Production for De-Risking Commercialisation
Jens Ducree, Professor of Microsystems, Dublin City University, Ireland

The presentation outlines the adoption of the platform based concept to microfluidic “Lab-on-a-Disc” systems developed in the recently founded Fraunhofer Project Centre for Embedded Bioanalytical Systems at Dublin City University.

10:45

Coffee & Networking in Exhibition Hall

11:15

Microfluidic Single Cell Sequencing
Yanyi Huang, Professor, Peking University, China

Microfluidic technologies can greatly facilitate the research at the single cell level, especially the genomic sequencing of single cells with greatly improved sensitivity, reproducibility, and accuracy.

11:45

Yole DéveloppementStatus of the Microfluidics Industry
Benjamin Roussel, Business Unit Manager of the Microfluidic & Medical Technologies (MedTech), Yole Développement

This year, KnowMade and Yole joined forces to get a comprehensive analysis of the microfluidics world in terms of market, technology and IP. This talk will present some of the results from their analysis to explain how and why microfluidic technologies are increasingly used, for which benefits. Benjamin Roussel will share his view of the strong maturation of the microfluidics industry, important strategic moves, race for molecular diagnostics, and IP strategy of main players.

12:15

Microfluidic Devices for Cryomicroscopy of Cells and Soft Materials
Thomas Burg, Group Leader, Max Planck Institute for Biophysical Chemistry, Germany

Light and electron microscopy can reveal amazing details of cell function and disease with nanometer resolution in single cells. Here I present a new microfluidic technology for imaging fast cellular dynamics by correlating live-cell imaging, cryo-light microscopy and electron microscopy.

12:45

Lunch & Networking in Exhibition Hall

13:15

Poster Viewing Session

13:30

STRATEC ConsumablesFree Workshop
Translating Customers Ideas into Microstructured Smart Polymer Parts Workshop
Iris Bergmair, Head of Sales & Business Development

14:15

Yield Engineering Systems, Inc.Technology Spotlight:
Need for Surface Tension Preparation for Microfluidic Devices
Ken Sautter, Director of Technology Development, Yield Engineering Systems, Inc.

This presentation will discuss the need for surface tension modification for successful microfluidic devices. Silane vapor phase deposition is the preferred method for coating surfaces, as the process environment can be tightly controlled, yielding repeatable, stable results. A process will be discussed offering multiple gas and plasma mode preparation plus multiple chemical reactants for vapor phase deposition, in order to prepare for optimum surface conditions.

14:30

Daniel IrimiaKeynote Presentation

Inflammation on a Chip
Daniel Irimia, Associate Professor, Surgery Department, Massachusetts General Hospital (MGH), Shriners Burns Hospital, and Harvard Medical School, United States of America

We designed and validated microfluidic technologies that measure the motility phenotype of neutrophils with higher precision than ever before, directly in a droplet of blood. We employed these new lab-on-a-chip devices to diagnose sepsis in patients with high accuracy.

15:15

Hahn-SchickardCentrifugal Step Emulsification Allows Miniaturized Digital Droplet-RPA,-LAMP and -PCR on the Centrifugal Microfluidic Platform
Felix von Stetten, Associate Director, Hahn-Schickard

A novel unit operation, designated as centrifugal step emulsification, enables droplet generation, DNA amplification and fluorescence detection within one single cavity. Results for absolute quantification of DNA by digital amplification are in good agreement with those obtained by a commercial dPCR system.

15:45

Coffee & Networking in Exhibition Hall

16:15

Microfluidics and Magnetic Particles for Cancer Clinical Research
Stephanie Descroix, Research Scientist, Institut Curie, France

16:45

A Conceptually New Photomicroreactor Design for Energy-efficient Solar Photochemistry
Timothy Noël, Associate Professor, Eindhoven University of Technology, Editor-in-Chief, The Journal of Flow Chemistry, Netherlands

We will present our results concerning a novel device integrating the luminescent solar concentrator (LSC) concept with photomicroreactors, allowing the direct use of solar light in photochemistry without the need for any intermediate energy conversion. This leaf-inspired photomicroreactor based on fluorescent dye-embedded polydimethylsiloxane collects sunlight, focuses the energy to a narrow wavelength region, and then transports that energy to embedded microchannels where the flowing reactants are converted.

17:15

Rapid Prototyping in Microfluidics: New Perspective by New Materials
Bastian Rapp, Principal Investigator and Head of NeptunLab, Karlsruhe Institute of Technology, Germany

This talk will highlight important improvements in additive manufacturing technology and materials for microfluidics.

17:45

Drinks Reception in Exhibition Hall

18:45

End of Day One

Thursday, 11 May 2017


Day Two
Session Chair: Bastian Rapp, Principal Investigator and Head of NeptunLab, Karlsruhe Institute of Technology, Germany

09:00

Translation of Microfluidic Technologies from the Laboratory to the Field
Joan Bienvenue, Executive Director, Applied Research Institute, University of Virginia, United States of America

This presentation will discuss commercialization of microfluidic technologies, the challenges and opportunities of taking lab-on-a-chip discoveries out of the laboratory and to applied use.

09:30

Thomas LaurellKeynote Presentation

Acoustofluidic Sample Processing Enables Novel Modalities for Medical Diagnostics
Thomas Laurell, Professor, Department of Biomedical Engineering, Lund University, Sweden

A new method for rapid enrichment and purification of extracellular vesicles (EV) based on acoustic seed trapping in disposable glass capillaries is presented, which provides EVs for biomarker analysis from minute biofluid volumes ˜ 10 uL in a few minutes without any need for ultracentrifugation.

10:15

New Approaches for Medical Diagnosis and Therapy Using Microfluidic Devices
Manabu Tokeshi, Professor, Hokkaido University, Japan

This presentation reports the development of a new platform of immunoassay device for detection of brain tumor. Using this devices, we succeeded in detection of grade II and III gliomas from patients within 15 min.

10:45

Coffee & Networking in Exhibition Hall

11:15

Acoustic Force Spectroscopy: Using Sound to Investigate Molecules and Cells
Gijs Wuite, Assistant Professor, Vrije Universiteit, Netherlands

Acoustic force spectroscopy (AFS) is a novel technique that makes use of an acoustic standing wave in a microfluidic chip to apply forces on cells or micron-sized beads tethered to molecules in order to study their mechanical properties

11:45

Label-Free Particle Sorting - Innovative Ways to Fractionate Cells Based on their Innate Properties
Jonas Tegenfeldt, Professor, Lund University, Sweden

Label-free sorting uses the inherent properties of the particles to divide them into different fractions. We will present results on sorting of cells and particles based not only on size but also shape, deformability, density and dielectric properties.

12:15

Ultrafast, Low-resource, Cost-effective Rapid-prototyping and Assembly Techniques for Accelerated Translation of Lab-On-Chip Microfluidic Devices: Novel and Revisited Concepts
Maiwenn Kersaudy-Kerhoas, Associate Professor, School of Engineering and Physical Sciences, Heriot-Watt University, United Kingdom

12:45

Lunch & Networking in Exhibition Hall

13:15

Poster Viewing Session

13:30

Zimmer and PeacockFree Workshop
The Fast Tracking Medical Diagnostics and Biosensor Technologies to the Market Workshop
Martin Peacock, Director

14:10

Venneos GmbHCell Analysis Beyond Vision Using CAN-Spectroscopy
Jonas Lehmann, Co-Founder & Managing Director, Venneos GmbH

14:15

Austrian Institute of Technology GmbHTechnology Spotlight:
Improving Peptide-Multiplexing Technology for Lab-On-Chip Autoantibody Based Diagnostics
Andreas Weinhaeusel, Senior Scientist, Austrian Institute of Technology GmbH

Detection of (tumor) autoantibodies present in patients’ blood against self-antigens, or aberrantly expressed proteins of tumor cells, presenting then tumor-associated antigens (TAAs) to the immune-system has a high potential for diagnostics. We have setup immunomics biomarker-discovery using protein- and peptide-microarrays as well as targeted multiplexed technologies for validation of these markers.

14:30

Elisabeth VerpoorteKeynote Presentation

Utilizing Microfluidic Components to Enhance Performance in Analytical Instrumentation
Elisabeth Verpoorte, Professor of Analytical Chemistry and Pharmaceutical Analysis, University of Groningen, Netherlands

Microfluidic devices may be implemented either as stand-alone tools or, increasingly, as components to impart additional function to existing instrumentation. This presentation will focus on two examples in which microfluidics is contributing to the development of miniaturized analytical instrumentation.

15:15

Lab-on-a-Chip with Incorporated Microarrays for the Detection of AMRs
Harald Peter, Research Scientist, Fraunhofer Institute for Cell Therapy and Immunology IZI-BB, Germany

Lab-on-a-chip multiplex assays allow a rapid identification of multiple parameters in an automated manner. Here we describe a lab-based preparation followed by a rapid and fully automated DNA microarray hybridization and readout in less than 10 minutes using the Fraunhofer in vitro diagnostics (IVD) platform to enable rapid identification of bacterial species and detection of antibiotic resistance. The use of DNA microarrays allows a fast adaptation of new biomarkers enabling the identification of different genes as well as single-nucleotide-polymorphisms (SNPs) within these genes. In this protocol we describe a DNA microarray developed for identification of Staphylococcus aureus and the mecA resistance gene.

15:45

Coffee & Networking in Exhibition Hall

16:15

Capillary-Based Microfluidics: from Concepts to Chips
Emmanuel Delamarche, Manager Precision Diagnostics, IBM Research - Zürich, Switzerland

This presentation describes the development of microfluidic functional elements for capillary-driven microfluidic chips. These chips can be used for immunoassays and connected to a smartphone for monitoring flow with sub-nanoliter precision.

16:45

Nanoplasmonic Biosensors: a Search for the Optimum Balance Between Optical Performance and Analyte Transport
Nicholas Scott Lynn, Research Scientist, The Institute of Photonics and Electronics of the Czech Academy of Sciences (IPE), Czech Republic

This presentation describes the development of microfluidic nanoplasmonic biosensors composed of arrays of metal nanoparticles, specifically focusing on the balance between optical performance (in terms of RI sensitivity) and analyte transport (in terms of the rate of analyte capture).

17:15

Close of Conference


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