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SELECTBIO Conferences Organoids and Organs-on-Chips Europe 2022

Organoids and Organs-on-Chips Europe 2022 Agenda


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Tuesday, 21 June 2022

00:00

Regina LuttgeKeynote Presentation

Title to be Confirmed
Regina Luttge, Professor, Eindhoven University of Technology, Netherlands

00:00

Nancy AllbrittonKeynote Presentation

Title to be Confirmed
Nancy Allbritton, Frank and Julie Jungers Dean of the College of Engineering and Professor of Bioengineering, University of Washington in Seattle, United States of America

00:00

Noo Li JeonKeynote Presentation

Title to be Confirmed.
Noo Li Jeon, Professor, Seoul National University, Korea South

00:00

Josué  SznitmanKeynote Presentation

Title to be Confirmed.
Josué Sznitman, Associate Professor, Technion – Israel Institute of Technology, Israel

00:00

Hervé TiriacKeynote Presentation

Title to be Confirmed.
Hervé Tiriac, Assistant Research Scientist, University of California-San Diego, United States of America

00:00

Peter ErtlKeynote Presentation

Title to be Confirmed.
Peter Ertl, Professor of Lab-on-a-Chip Systems, Vienna University of Technology, Austria

00:00

Séverine Le GacKeynote Presentation

Title to be Confirmed.
Séverine Le Gac, Professor, Applied Microfluidics for Bioengineering Research, MESA+ Institute for Nanotechnology, University of Twente, Netherlands

00:00

Andries D. van der MeerKeynote Presentation

Title to be Confirmed.
Andries D. van der Meer, Associate Professor, Scientific lead, Organ-on-Chip Center Twente, University of Twente, Netherlands

00:00

Title to be Confirmed.
Marcel Karperien, Professor, University of Twente, Netherlands

00:00

Midbrain Organoids for Parkinson’s Disease Modeling
Cláudia Saraiva, Post-Doctoral Researcher, University of Luxembourg, Luxembourg

Parkinson’s disease (PD) is the second most prevalent disorder worldwide and its incidence is rising. Nevertheless, few advances in PD treatment have been observed. Therefore, understanding of PD associated mechanisms using novel complex and translatable models is timely. In our lab, we developed 3D cultures that resemble the human midbrain (midbrain organoids, MOs) through guided differentiation of induced pluripotent stem cells (iPSCs). The MOs are a complex system in terms of cellular composition and structural organization. Using PD patient-derived MOs we demonstrate that not only they resemble the midbrain organization but they also recapitulate key features of the PD pathology, such as dopaminergic neuron differentiation. Using this technology, we are currently investigating the role of the recently described Miro1 protein in dopaminergic differentiation in PD. Using high content imaging and western blotting we observed that a gain-of-function in Miro1 results in lower levels of dopaminergic neuros. Also Miro1-mutant MOs show a mitochondrial impairment when compared with healthy controls. Altogether, this work shows the importance of Miro1 in the pathology of Parkinson, and shed light into a possible novel and convergent pathway in PD.

00:00

George TruskeyKeynote Presentation

Title to be Confirmed.
George Truskey, R. Eugene and Susie E. Goodson Professor of Biomedical Engineering, Duke University, United States of America

00:00

Matthias von HerrathKeynote Presentation

Title to be Confirmed.
Matthias von Herrath, Vice President and Senior Medical Officer, Novo Nordisk, Professor, La Jolla Institute, United States of America

00:00

Elisabeth VerpoorteKeynote Presentation

Title to be Confirmed.
Elisabeth Verpoorte, Professor of Analytical Chemistry and Pharmaceutical Analysis, University of Groningen, Netherlands


Agenda is not currently available
Add to Calendar ▼2022-06-21 00:00:002022-06-22 00:00:00Europe/LondonOrganoids and Organs-on-Chips Europe 2022Organoids and Organs-on-Chips Europe 2022 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com