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SELECTBIO Conferences Extracellular Vesicles (EVs): Technologies & Biological Investigations


Defining the Role of Small Extracellular Vesicles in Lymph Node Pre-metastatic Niche Formation

Hector Peinado, Head, Spanish National Cancer Research Centre (CNIO)

We have analyzed the dynamics of tumor-derived small EVs (sEVs) in the lymphatic system and their role establishing the pre-metastatic niche formation in sentinel lymph nodes. Our data shows how both tumor intrinsic and extrinsic factors such as tumor-secreted sEVs are involved in lymphangiogenesis and pre-metastatic niche formation in sentinel lymph nodes through a neurotrophin receptor-dependent mechanism favoring metastatic spread in melanoma.

Add to Calendar ▼2021-12-13 00:00:002021-12-15 00:00:00Europe/LondonExtracellular Vesicles (EVs): Technologies and Biological InvestigationsExtracellular Vesicles (EVs): Technologies and Biological Investigations in Coronado Island, CaliforniaCoronado Island,