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SELECTBIO Conferences Organoids & Organs-on-Chips 2021


Generation of iPSC-derived 3D Neurospheres for Modeling Retroviral Infection and EV-mediated Repair

Heather Branscome, Post-Doctoral Scientist, George Mason University

We report the generation of iPSC-derived neurospheres and show that these cultures are permissive to HIV-1 infection. In addition, we examine the functional effects of stem cell extracellular vesicles (EVs) on HIV-1 infected neurospheres. Our data demonstrates the feasibility of iPSC-derived neurospheres for modeling HIV-1 infection and highlights the potential of stem cell EVs for rescuing cellular damage.

Add to Calendar ▼2021-12-13 00:00:002021-12-15 00:00:00Europe/LondonOrganoids and Organs-on-Chips 2021Organoids and Organs-on-Chips 2021 in Coronado Island, CaliforniaCoronado Island,