Abstract

A Mesh Culture Technique for Fabricating Organ-on-chip and Organoids

Kennedy Okeyo, Senior Lecturer, Institute for Frontier Life and Medical Sciences, Kyoto University

With increasing focus on organ-on-a-chip and organoids, the ability to fabricate standalone tissues in a microfluidic platform is increasingly becoming important. This talk will introduce a mesh culture technique, dubbed “The Shoji Technique”, which enables fabrication of standalone tissues compatible with a microfluidic platform. Application toward the realization of organ-on-a-chip capable of recapitulating direct crosstalk between different constituting cell layers of an organ (e.g. epithelial and endothelial layers) will be demonstrated.