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SELECTBIO Conferences Epigenetics in Drug Discovery

Anja Groth's Biography

Anja Groth, Group Leader, University of Copenhagen

Anja Groth is a professor at the Biotech Research and Innovation Centre (BRIC), Health and Medical Faculty, University of Copenhagen. AG received her PhD in Molecular Biology from University of Copenhagen in 2004 for research on genome maintenance with Drs. Lukas and Bartek (Danish Cancer Society). In 2005, AG joined Dr. Almouzni (Institut Curie, Paris) as a post.doc to work on histone dynamics and DNA replication. AG established her research group at BRIC in 2008, supported by a Lundbeck Foundation Junior Group Leader Fellowship and an ERC starting grant. AG received tenure in 2013 and became a full professor at BRIC in 2016. Her research group includes about 14 PhDs and, and is supported by highly competitive national and international funding including an ERC consolidator grant. She serves on the Danish Medical Research Council and has been awarded several research prizes and was elected a member of the Royal Danish Academy of Sciences and Letters in 2016. The Groth group is applying cutting-edge proteomic and genomic approaches as well as structure-function analysis to understand molecular mechanisms of chromatin replication and their implications for genome and epigenome maintenance.

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Targeting Homologous Recombination Repair In Cancer: Structure-Based Drug Design On A New Histone Reader

Monday, 6 March 2017 at 10:15

Add to Calendar ▼2017-03-06 10:15:002017-03-06 11:15:00Europe/LondonTargeting Homologous Recombination Repair In Cancer: Structure-Based Drug Design On A New Histone

We have identified the TONSL–MMS22L homologous recombination complex as a reader of histone H4 tails unmethylated at K20 (H4K20me0). Targeting of the TONSL histone reader domain thus offers a unique opportunity to target homologous recombination in cancer therapy.

Add to Calendar ▼2017-03-06 00:00:002017-03-07 00:00:00Europe/LondonEpigenetics in Drug