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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics Europe 2022

Holger Schmidt's Biography

Holger Schmidt, Narinder Kapany Professor of Electrical Engineering, University of California-Santa Cruz

Holger Schmidt received the Ph.D. degree in electrical and computer engineering from the University of California Santa Barbara and served as a Postdoctoral Fellow at M.I.T. He is currently the Narinder Kapany Chair of Optoelectronics and Distinguished Professor of Electrical and Computer Engineering at UC Santa Cruz. He directs the W.M. Keck Center for Nanoscale Optofluidics and has served as the Associate Dean for Research in the Baskin School of Engineering. His research interests cover a broad range in photonics and integrated optics, including optofluidic devices, nanopore sensors, nano-magneto-optics, spintronic devices, and ultrafast optics. He has authored more than 400 publications, several book chapters, and co-edited the CRC Handbook of Optofluidics. He is a Fellow of the National Academy of Inventors, the IEEE and the Optical Society of America. He received an NSF Career Award, a Keck Futures Nanotechnology Award, and the Engineering Achievement Award by the IEEE Photonics Society.

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Ultra-Sensitive Optofluidic Platform for Point-of-Care Molecular Diagnostics

Tuesday, 21 June 2022 at 10:00

Add to Calendar ▼2022-06-21 10:00:002022-06-21 11:00:00Europe/LondonUltra-Sensitive Optofluidic Platform for Point-of-Care Molecular DiagnosticsLab-on-a-Chip and Microfluidics Europe 2022 in Rotterdam, The NetherlandsRotterdam, The

Lab-on-chip systems can form the basis for next-generation molecular biosensors for point-of-care use. In order to fulfill this potential, they need to combine excellent specificity and sensitivity with speed, robustness, and low cost. I will describe a waveguide-based optofluidic platform that is ideal for this purpose. Specifically, I will review ultrasensitive performance using the example of  fluorescence and label-free detection of SARS-CoV-2 from clinical nasal swab samples with single molecule sensitivity. Multiplex detection of single viral antigens is demonstrated along with dual detection of viral DNA and antigen as well as label-free nanopore sensing of single RNAs with 2,000x enhanced detection rate. In addition, I will discuss approaches geared at adapting this platform for point-of-case use, including novel signal analysis algorithms and implementation of real-time analysis of single-molecule fluorescence signals.

Add to Calendar ▼2022-06-21 00:00:002022-06-22 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Europe 2022Lab-on-a-Chip and Microfluidics Europe 2022 in Rotterdam, The NetherlandsRotterdam, The