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SELECTBIO Conferences Single Cell Analysis Summit 2018

Larry Xi's Biography

Larry Xi, CEO and CSO, Digenomix Corp

Dr. Larry Xi worked on PCR-related technologies for more than a dozen years following a career path of “M-B-A” (acronym of MJ Research, BioRad, and ABI). These three companies once had combined 80% of PCR market. In 2013, he joined Fluidigm In his after-Life (when ABI merged into Life Technologies). He invented BIG (barcoding-in-Genome) technology when working for Fluidigm. In 2017, he acquired the right to BIG and formed Digenomix Corp, and has served as CEO and CSO.

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Towards Single-cell DNA Digital Sequencing

Tuesday, 2 October 2018 at 16:00

Add to Calendar ▼2018-10-02 16:00:002018-10-02 17:00:00Europe/LondonTowards Single-cell DNA Digital SequencingSingle Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island,

Single-cell DNA sequencing has been shown to gain greater insights into the clonal structures of heterogeneous cancer tissues that bulk DNA sequencing has never been able to resolve.  However, biased whole genome amplifications from single-cell DNA reduce the resolution and the potential of this approach.   We proposed a scheme, BIG (Barcoding-In-Genome), that could increase the resolution by turning the analog mode of DNA sequencing into digital mode.  This digital mode will give exact, absolute copy number for every gene and can only be achieved on single-cell platforms.

Add to Calendar ▼2018-10-02 00:00:002018-10-03 00:00:00Europe/LondonSingle Cell Analysis Summit 2018Single Cell Analysis Summit 2018 in Coronado Island, CaliforniaCoronado Island,