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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics Europe 2021

Dino Di Carlo's Biography



Dino Di Carlo, Professor and Vice Chair of Bioengineering, University of California-Los Angeles

Dino Di Carlo received his B.S. in Bioengineering from the University of California, Berkeley in 2002 and received a Ph.D. in Bioengineering from the University of California, Berkeley and San Francisco in 2006. From 2006-2008 he conducted postdoctoral studies in the Center for Engineering in Medicine at Harvard Medical School. He has been on the faculty in the Department of Bioengineering at UCLA since 2008 and now as Professor of Bioengineering and Mechanical Engineering serves as the Vice Chair of the Department and as the director of the Cancer Nanotechnology Program in the Jonsson Comprehensive Cancer Center. His research pioneered the use of inertial fluid dynamic effects for the control, separation, and analysis of cells in microfluidic devices. His recent work extends into numerous other fields of biomedicine and biotechnology including directed evolution, cell analysis for rapid diagnostics, new amplified molecular assays, next generation biomaterials, and phenotypic drug screening. He has also been a leader in technology entrepreneurship: He co-founded and currently serves on the board of directors of five companies that are commercializing UCLA intellectual property developed in his lab (CytoVale, Vortex Biosciences, Tempo Therapeutics, Forcyte Biotechnologies and Ferrologix). Among other honors he received the Presidential Early Career Award for Scientists and Engineers (PECASE) and was elected a Fellow of the American Institute for Medical and Biological Engineering in 2016, was elected a Fellow of the Royal Society of Chemistry (FRSC) in 2014, was awarded the National Science Foundation (NSF) Faculty Early Career Development award and the U.S. Office of Naval Research (ONR) Young Investigator Award, the Packard Fellowship and Defense Advanced Research Projects Agency (DARPA) Young Faculty Award, and received the National Institutes of Health (NIH) Director’s New Innovator Award and Coulter Translational Research Award.

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Sorting of Single Cells Based on Secreted Products Using Lab on a Particle Technology

Monday, 28 June 2021 at 16:30

Add to Calendar ▼2021-06-28 16:30:002021-06-28 17:30:00Europe/LondonSorting of Single Cells Based on Secreted Products Using Lab on a Particle TechnologyLab-on-a-Chip and Microfluidics Europe 2021 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

Sorting cells based on secreted products enables the discovery of antibodies, the development of cell lines producing recombinant products, and the selection of functional cells for cell therapies. However, approaches to rapidly analyze and sort viable cells based on secretions are not easily accessible. I will discuss nanovial technology that enables the isolation of individual cells in cavities of 3D-shaped hydrogel particles massively in parallel. These hydrogel particles, or nanovials, act as small wells to bind and accumulate secreted products at high concentrations, and enable washing and labeling steps. The nanovials and attached cells can then be sorted based on their secretions and their functions using standard FACS systems. This approach promises to democratize the ability to discover and manufacture drugs and cell therapies.


Add to Calendar ▼2021-06-28 00:00:002021-06-30 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Europe 2021Lab-on-a-Chip and Microfluidics Europe 2021 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com