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SELECTBIO Conferences Stem Cells for Drug Discovery & Toxicity Screening 2017

Mark Bradley's Biography

Mark Bradley, Professor, Schools of Chemistry and Medicine, University of Edinburgh

Mark received his doctorate from the University of Oxford in 1989, followed by post-doctoral studies at Harvard and returning to the UK as a Royal Society University Research Fellow (University of Southampton). In 1997 he was made a Professor of Combinatorial Chemistry setting up the UK’s Centre for Combinatorial Chemistry. In 2005 he moved to the University of Edinburgh, where he is now Director of a £10M Interdisciplinary Research Collaboration in the area of Optical Molecular Imaging. He is also PI on a Doctorial Training Centre (60PhD) in Optical Imaging with Entrepreneurship) and holds an ERC advanced grant on “SmartMaterials” for cellular control.

He has been elected to fellowships of the Royal Society of Edinburgh. In 2011 he was awarded the Chancellors Award – the highest research award of the University of Edinburgh. In 2012 he was awarded an honoree Professorship by Changzhou University, China. He is a co-founder of Ilika Technologies (2004), DestiNA Technologies (2010) and Edinburgh Molecular Imaging (2014).

Three research themes dominate in his group at this time:

(i). The development and exploitation of polymer microarray technology for the identification and application of polymers for controlling and modulating stem cells
(ii). The development of “smart” fluorescent reporters for in vivo based optical molecular imaging
(iii). In vivo catalytic chemistry

Mark Bradley Image

Substrates for Generating Cancer Stem Cells and Highly Functional Hepatocytes

Tuesday, 11 July 2017 at 13:30

Add to Calendar ▼2017-07-11 13:30:002017-07-11 14:30:00Europe/LondonSubstrates for Generating Cancer Stem Cells and Highly Functional HepatocytesStem Cells for Drug Discovery and Toxicity Screening 2017 in Boston, USABoston,

In my talk I will introduce polymer microarray technology; including our inkjet mediated fabrication methodologies (which allows over 7000 different substrates to be made on a single glass slide) and describe how this approach has been used in a large number of stem cell based applications, notably:

(i). The use of polymer microarray technology to discover a novel thermo-responsive chemically-defined hydrogel for long term culture of human embryonic stem cells (Nature Communication, 2013) and mesenchymal adipose derived stem cells (Biomaterials, 2014)

(ii). Polymer discovery that were able to support highly functional hESC-derived hepatocyte like cells (as active as primary human hepatoctyes) (with David Hay see: Stem Cell Res, 2011 and WO2010106345)

(iii). The discovery and application of a substrate able to “lock-down” CSC’s in their CSC state

Add to Calendar ▼2017-07-10 00:00:002017-07-11 00:00:00Europe/LondonStem Cells for Drug Discovery and Toxicity Screening 2017Stem Cells for Drug Discovery and Toxicity Screening 2017 in Boston, USABoston,