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SELECTBIO Conferences Lab-on-a-Chip and Microfluidics Europe 2021

Andrew J deMello's Biography



Andrew J deMello, Professor of Biochemical Engineering & Institute Chair, ETH Zürich

Andrew is currently Professor of Biochemical Engineering in the Department of Chemistry and Applied Biosciences at ETH Zürich and Head of the Institute for Chemical and Bioengineering. Prior to his arrival in Zurich he was Professor of Chemical Nanosciences and Head of the Nanostructured Materials and Devices Section in the Chemistry Department at Imperial College London. His research interests cover a broad range of activities in the general area of microfluidics and nanoscale science. Primary specializations include the development of microfluidic devices for high-throughput biological and chemical analysis, ultra-sensitive optical detection techniques, nanofluidic reaction systems for chemical synthesis, novel methods for nanoparticle synthesis, the exploitation of semiconducting materials in diagnostic applications, the development of intelligent microfluidics and the processing of living organisms.

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Optofluidic Imaging Flow Cytometry

Monday, 28 June 2021 at 11:00

Add to Calendar ▼2021-06-28 11:00:002021-06-28 12:00:00Europe/LondonOptofluidic Imaging Flow CytometryLab-on-a-Chip and Microfluidics Europe 2021 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

I will present recent activities aimed at developing novel microfluidic imaging flow cytometers for blur-free cellular analysis at throughputs exceeding 100,000 cells per second. By combining passive (inertial or viscoelastic) focusing of cells in parallel microchannels with stroboscopic illumination, such chip-based cytometers are able to extract multi-colour fluorescence and bright-field images of single cells moving at high linear velocities. This in turn allows accurate sizing of individual cells, intracellular localization and analysis of heterogeneous cell suspensions. The methods are showcased through the rapid enumeration of apoptotic cells, high-throughput discrimination cell cycle phases and localization of p-bodies. Additionally, the optofluidic platforms can be integrated with weakly-supervised deep learning methods to perform rapid diagnosis of diseases, such as cutaneous T-cell lymphoma.


Add to Calendar ▼2021-06-28 00:00:002021-06-30 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics Europe 2021Lab-on-a-Chip and Microfluidics Europe 2021 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com