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SELECTBIO Conferences Lab-on-a-Chip & Microfluidics World Congress 2017

Sergey Shevkoplyas's Biography

Sergey Shevkoplyas, Associate Professor, Biomedical Engineering, University of Houston

Dr. Shevkoplyas is a biomedical engineer with core expertise in blood microfluidics. His primary research interests are the development and clinical translation of high-throughput microfluidic devices and single-cell analysis tools in the field of blood storage and transfusion medicine. An additional significant thrust of his research program is the development of enabling technology for low-cost, point-of-care diagnostics in resource-limited settings. Dr. Shevkoplyas is an Associate Professor in the Department of Biomedical Engineering at the University of Houston. He received his B.S. and M.S. degrees in Applied Mathematics & Physics from Moscow Institute of Physics & Technology, Russia in 2000, and his Ph.D. degree in Biomedical Engineering from Boston University in 2005. Dr. Shevkoplyas also completed a postdoctoral fellowship in Chemistry and Chemical Biology at Harvard University (2005 – 2008), and served on the faculty of Tulane University as an Assistant and Associate Professor of Biomedical Engineering (2008 – 2013). Dr. Shevkoplyas has authored 40 peer-reviewed articles, published two book chapters and is an inventor on 14 U.S. patents and patent applications. His research has been funded by the National Blood Foundation, the Bill & Melinda Gates Foundation, U.S. Army and the National Institutes of Health, including the recently awarded 2012 NIH Director's Transformative Research Award (T-R01).

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Controlled Incremental Filtration: A Novel Microfluidic Approach for High-Throughput Separation of Circulating Cells from Whole Blood

Wednesday, 4 October 2017 at 08:30

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Separation of circulating cells from whole blood and other blood-derived samples is an important part of a broad range of medical applications.  A versatile microfluidic approach that is suitable for a large range of particle sizes and high levels of enrichment, with a volumetric throughput sufficient for large-scale applications, has yet to emerge.  Most microfluidic technologies developed for separating circulating cells from blood have been of very little use for large volume processing because of relatively low volumetric throughputs, small minimal feature sizes, and the need for exceedingly dilute samples.  Controlled incremental filtration (CIF), a new microfluidic approach we recently developed, enables a microfluidic device with a relatively small footprint to operate at practical throughputs (>15mL/min), have distinctly manufacturable minimal feature sizes (>20µm), process blood samples without dilution, and concentrate cells of interest >40-fold.  This talk will describe the use of CIF-based devices for leukoreduction of platelet rich plasma, and extraction of lymphocytes from whole blood.

Add to Calendar ▼2017-10-02 00:00:002017-10-04 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics World Congress 2017Lab-on-a-Chip and Microfluidics World Congress 2017 in Coronado Island, CaliforniaCoronado Island,